PSMB11 Antikörper (C-Term)

Produktnummer ABIN2790679

Produktdetails anti-PSMB11 Antikörper

Target: PSMB11 (Proteasome (Prosome, Macropain) Subunit, beta Type, 11 (PSMB11))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMB11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: HVRESGWEHV SRSDACVLYV ELQKLLEPEP EEDASHAHPE PATAHRAAED

Homologie: Human: 100%, Rat: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against PSMB11. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PSMB11

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 300 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PSMB11

Target: PSMB11 (Proteasome (Prosome, Macropain) Subunit, beta Type, 11 (PSMB11))

Andere Bezeichnung: PSMB11 (PSMB11 Produkte)

Synonyme: BETA5T antikoerper, 5830406J20Rik antikoerper, beta5t antikoerper, proteasome subunit beta 11 antikoerper, proteasome (prosome, macropain) subunit, beta type, 11 antikoerper, PSMB11 antikoerper, Psmb11 antikoerper

Hintergrund: Proteasomes generate peptides that are presented by major histocompatibility complex (MHC) I molecules to other cells of the immune system. Proteolysis is conducted by 20S proteasomes, complexes of 28 subunits arranged as a cylinder in 4 heteroheptameric rings: alpha-1 to -7, beta-1 to -7, beta-1 to -7, and alpha-1 to -7. The catalytic subunits are beta-1, beta-2), and beta-5 (PSMB5, MIM 600306). Three additional subunits, beta-1i, beta-2i, and beta-5i, are induced by gamma-interferon and are preferentially incorporated into proteasomes to make immunoproteasomes. PSMB11, or beta-5t, is a catalytic subunit expressed exclusively in cortical thymic epithelial cells .
Alias Symbols: BETA5T
Protein Size: 300

Molekulargewicht: 33 kDa

Gen-ID: 122706

NCBI Accession: NM_001099780, NP_001093250

UniProt: A5LHX3