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PSMB11 Antikörper (C-Term)

PSMB11 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB28790 unconjugated
Produktnummer ABIN655286
  • Target Alle PSMB11 Produkte
    PSMB11 (Proteasome (Prosome, Macropain) Subunit, beta Type, 11 (PSMB11))
    Bindungsspezifität
    • 7
    • 7
    • 6
    AA 250-278, C-Term
    Reaktivität
    • 17
    • 3
    • 2
    Human
    Wirt
    • 17
    • 1
    Kaninchen
    Klonalität
    • 17
    • 1
    Polyklonal
    Konjugat
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser PSMB11 Antikörper ist unkonjugiert
    Applikation
    • 18
    • 14
    • 13
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This PSMB11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250-278 amino acids from the C-terminal region of human PSMB11.
    Klon
    RB28790
    Isotyp
    Ig Fraction
  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:50~100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    PSMB11 (Proteasome (Prosome, Macropain) Subunit, beta Type, 11 (PSMB11))
    Andere Bezeichnung
    PSMB11 (PSMB11 Produkte)
    Synonyme
    BETA5T antikoerper, 5830406J20Rik antikoerper, beta5t antikoerper, proteasome subunit beta 11 antikoerper, proteasome (prosome, macropain) subunit, beta type, 11 antikoerper, PSMB11 antikoerper, Psmb11 antikoerper
    Hintergrund
    Proteasomes generate peptides that are presented by major histocompatibility complex (MHC) I molecules to other cells of the immune system. Proteolysis is conducted by 20S proteasomes, complexes of 28 subunits arranged as a cylinder in 4 heteroheptameric rings: alpha-1 to -7, beta-1 to -7, beta-1 to -7, and alpha-1 to -7. The catalytic subunits are beta-1 (PSMB6, MIM 600307), beta-2 (PSMB7, MIM 604030), and beta-5 (PSMB5, MIM 600306). Three additional subunits, beta-1i (PSMB9, MIM 177045), beta-2i (PSMB10, MIM 176847), and beta-5i (PSMB8, MIM 177046), are induced by gamma-interferon (IFNG, MIM 147570) and are preferentially incorporated into proteasomes to make immunoproteasomes. PSMB11, or beta-5t, is a catalytic subunit expressed exclusively in cortical thymic epithelial cells (Murata et al., 2007 [PubMed 17540904]).
    Molekulargewicht
    32530
    Gen-ID
    122706
    NCBI Accession
    NP_001093250
    UniProt
    A5LHX3
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