TNIP3 Antikörper (N-Term)

Produktnummer ABIN2790314

Produktdetails anti-TNIP3 Antikörper

Target: TNIP3 (TNFAIP3 Interacting Protein 3 (TNIP3))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNIP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: YERKVAELKT KLDAAERFLS TREKDPHQRQ RKDDRQREDD RQRDLTRDRL

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TNIP3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human TNIP3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 256 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TNIP3

Target: TNIP3 (TNFAIP3 Interacting Protein 3 (TNIP3))

Andere Bezeichnung: TNIP3 (TNIP3 Produkte)

Synonyme: ABIN-3 antikoerper, LIND antikoerper, 9030611K07Rik antikoerper, TNIP3 antikoerper, TNFAIP3 interacting protein 3 antikoerper, TNIP3 antikoerper, Tnip3 antikoerper

Hintergrund: TNIP3 binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding.
Alias Symbols: ABIN-3, FLJ21162, LIND
Protein Interaction Partner: ZBTB8A, NOTCH2NL, KRTAP10-3, KRTAP10-8, KRT40, LZTS2, TNIP1, DAZAP2, TAX1BP1, UBC, TNFAIP3, NFKB1,
Protein Size: 256

Molekulargewicht: 27 kDa

Gen-ID: 79931

NCBI Accession: NM_001128843

UniProt: Q96KP6

Pathways: Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin