GADD34 Antikörper (N-Term)

Produktnummer ABIN2789598

Produktdetails anti-GADD34 Antikörper

Target: GADD34 (PPP1R15A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A (PPP1R15A))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GADD34 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: GMYGEREATS VPRGQGSQFA DGQRAPLSPS LLIRTLQGSD KNPGEEKAEE

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PPP1R15A. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 674 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GADD34

Target: GADD34 (PPP1R15A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A (PPP1R15A))

Andere Bezeichnung: PPP1R15A (PPP1R15A Produkte)

Synonyme: 9630030H21 antikoerper, Gadd34 antikoerper, Myd116 antikoerper, GADD34 antikoerper, Peg-3 antikoerper, RGD1624209 antikoerper, protein phosphatase 1 regulatory subunit 15A antikoerper, protein phosphatase 1, regulatory (inhibitor) subunit 15A antikoerper, protein phosphatase 1, regulatory subunit 15A antikoerper, PPP1R15A antikoerper, Ppp1r15a antikoerper

Hintergrund: This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation.
Alias Symbols: GADD34
Protein Interaction Partner: Dlg4, ZNF512B, PPP1CA, CTBP2, SMAD7, CAND1, COPS5, CUL3, RAD21, CUEDC2, IKBKB, HABP4, PPP1CC, PPP1R1A, TSN, KIF3A, EIF2S1, BCAR1, POU3F3, SMARCB1, BAG1, LYN, KMT2A, HSPA1A, GLC7, PPP1CB, HSPA8,
Protein Size: 674

Molekulargewicht: 74 kDa

Gen-ID: 23645

NCBI Accession: NM_014330, NP_055145

UniProt: O75807

Pathways: ER-Nucleus Signaling, Unfolded Protein Response