MUS81 Antikörper (Middle Region)

Produktnummer ABIN2788793

Produktdetails anti-MUS81 Antikörper

Target: MUS81 (MUS81 Endonuclease Homolog (MUS81))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MUS81 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PEGLELAQKL AESEGLSLLN VGIGPKEPPG EETAVPGAAS AELASEAGVQ

Homologie: Human: 100%, Rat: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against MUS81. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 551 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MUS81

Target: MUS81 (MUS81 Endonuclease Homolog (MUS81))

Andere Bezeichnung: MUS81 (MUS81 Produkte)

Synonyme: CG3026 antikoerper, Dmel\\CG3026 antikoerper, EG:BACR7A4.16 antikoerper, MUS81 antikoerper, GB15332 antikoerper, ARABIDOPSIS THALIANA MMS AND UV SENSITIVE 81 antikoerper, ATMUS81 antikoerper, F6I18.220 antikoerper, F6I18_220 antikoerper, MMS AND UV SENSITIVE 81 antikoerper, SLX3 antikoerper, slx3 antikoerper, 1200008A18Rik antikoerper, AI182501 antikoerper, AW045863 antikoerper, wu:fc26g01 antikoerper, zgc:66489 antikoerper, zgc:91801 antikoerper, CG3026 gene product from transcript CG3026-RA antikoerper, MUS81 structure-specific endonuclease subunit antikoerper, crossover junction endonuclease MUS81 antikoerper, Restriction endonuclease, type II-like superfamily protein antikoerper, Mus81p antikoerper, Holliday junction resolvase subunit Mus81 antikoerper, MUS81 protein antikoerper, hypothetical protein antikoerper, mus81 antikoerper, MUS81 antikoerper, LOC725951 antikoerper, Mus81 antikoerper, CAALFM_C600540WA antikoerper

Hintergrund: MUS81 interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. It may be required in mitosis for the processing of stalled or collapsed replication forks.
Alias Symbols: FLJ21012, FLJ44872, SLX3
Protein Interaction Partner: SLX4, vpr, EME1, PLK1, FBXL5, SLX1A, WEE1, EME2, SUMO2, SLX1B, MUS81, CHEK2, TERT, TERF2,
Protein Size: 551

Molekulargewicht: 61 kDa

Gen-ID: 80198

NCBI Accession: NM_025128, NP_079404

UniProt: Q96NY9

Pathways: DNA Reparatur