HVEM Antikörper (Middle Region)
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- Target Alle HVEM (TNFRSF14) Antikörper anzeigen
- HVEM (TNFRSF14) (Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser HVEM Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- VCGCSPGHFC IVQDGDHCAA CRAYATSSPG QRVQKGGTES QDTLCQNCPP
- Homologie
- Human: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against TNFRSF14. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product TNFRSF14 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 283 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- HVEM (TNFRSF14) (Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14))
- Andere Bezeichnung
- TNFRSF14 (TNFRSF14 Produkte)
- Synonyme
- ATAR antikoerper, CD270 antikoerper, HVEA antikoerper, HVEM antikoerper, LIGHTR antikoerper, TR2 antikoerper, Atar antikoerper, HveA antikoerper, Hvem antikoerper, Tnfrs14 antikoerper, TNF receptor superfamily member 14 antikoerper, tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) antikoerper, Tnfrsf14 antikoerper, TNFRSF14 antikoerper
- Substanzklasse
- Viral Protein
- Hintergrund
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The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor was identified as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV viral envelope glycoprotein D (gD) to this receptor protein has been shown to be part of the viral entry mechanism. The cytoplasmic region of this receptor was found to bind to several TRAF family members, which may mediate the signal transduction pathways that activate the immune response.
Alias Symbols: ATAR, HVEA, HVEM, LIGHTR, TR2, CD270
Protein Interaction Partner: BTLA, CD160, APP, RAD21, WDR73, ITFG1, KIAA1377, UBQLN4, DRAP1, MBTPS1, DYNLL1, DGKD, SERPINA4, NDUFS2, IMPA2, ZBTB48, A2M, CHD3, HDAC3, HDAC4, TNFSF14, TNFSF13, TNFRSF14, NRIP1, TRAF5, TRAF3, TRAF2, TRAF1, VIM, LTA, ESR1, UGGT1, SEC11A, GCN1L1, PDIA6, P4
Protein Size: 283 - Molekulargewicht
- 31 kDa
- Gen-ID
- 8764
- NCBI Accession
- NM_003820, NP_003811
- UniProt
- Q92956
- Pathways
- Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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