HCK Antikörper (C-Term)
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- Target Alle HCK Antikörper anzeigen
- HCK (Hemopoietic Cell Kinase (HCK))
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Bindungsspezifität
- C-Term
- Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser HCK Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- LVKLHAVVTK EPIYIITEFM AKGSLLDFLK SDEGSKQPLP KLIDFSAQIA
- Homologie
- Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 79%, Rat: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against HCK. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human HCK
- Top Product
- Discover our top product HCK Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 504 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- HCK (Hemopoietic Cell Kinase (HCK))
- Andere Bezeichnung
- HCK (HCK Produkte)
- Synonyme
- laloo antikoerper, HCK antikoerper, MGC107870 antikoerper, JTK9 antikoerper, p59Hck antikoerper, p61Hck antikoerper, AI849071 antikoerper, Bmk antikoerper, Hctk antikoerper, p56Hck antikoerper, HCK proto-oncogene, Src family tyrosine kinase L homeolog antikoerper, HCK proto-oncogene, Src family tyrosine kinase antikoerper, hemopoietic cell kinase antikoerper, hck.L antikoerper, HCK antikoerper, hck antikoerper, Hck antikoerper
- Hintergrund
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The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon.
Alias Symbols: JTK9, p59Hck, p61Hck
Protein Interaction Partner: NOTCH2NL, KRTAP10-9, KRT40, GOPC, MTUS2, SPRR2A, STAT3, ACTB, Mbp, MED28, RUFY1, WNT2, HSP90AA1, ERBB3, ABL2, CBL, APP, PAK2, nef, TNK2, ADAM15, CREBBP, FASLG, SH3KBP1, KHDRBS1, MYC, UBC, SRC, MAP4K5, CHST15, ELMO1, SF3B3, EVL, IRF2BPL, SH3BP1, INPP5D, AG
Protein Size: 504 - Molekulargewicht
- 55 kDa
- Gen-ID
- 3055
- NCBI Accession
- NM_001172131, NP_001165602
- UniProt
- P08631
- Pathways
- Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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