TTF1 Antikörper (Middle Region)

Produktnummer ABIN2788733

Produktdetails anti-TTF1 Antikörper

Target: TTF1 (Transcription Termination Factor, RNA Polymerase I (TTF1))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TTF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KNSESTLFDS VEGDGAMMEE GVKSRPRQKK TQACLASKHV QEAPRLEPAN

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TTF1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TTF1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 905 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TTF1

Target: TTF1 (Transcription Termination Factor, RNA Polymerase I (TTF1))

Andere Bezeichnung: TTF1 (TTF1 Produkte)

Synonyme: TTF-1 antikoerper, TTF-I antikoerper, AV245725 antikoerper, RGD1565673 antikoerper, transcription termination factor 1 antikoerper, transcription termination factor, RNA polymerase I antikoerper, TTF1 antikoerper, Ttf1 antikoerper

Hintergrund: This gene encodes a transcription termination factor that is localized to the nucleolus and plays a critical role in ribosomal gene transcription. The encoded protein mediates the termination of RNA polymerase I transcription by binding to Sal box terminator elements downstream of pre-rRNA coding regions. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. This gene shares the symbol/alias 'TFF1' with another gene, NK2 homeobox 1, also known as thyroid transcription factor 1, which plays a role in the regulation of thyroid-specific gene expression.
Alias Symbols: TTF-1, TTF-I
Protein Interaction Partner: SMAD7, SMAD1, SIRT7, UBC, MDM2, CDKN2A, BAZ2A, KAT2B, PTRF, NFATC3,
Protein Size: 905

Molekulargewicht: 103 kDa

Gen-ID: 7270

NCBI Accession: NM_007344, NP_031370

UniProt: Q15361

Pathways: Thyroid Hormone Synthesis, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour