PCSK2 Antikörper (Middle Region)

Produktnummer ABIN2788115

Produktdetails anti-PCSK2 Antikörper

Target: PCSK2 (Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCSK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LASTFSNGRK RNPEAGVATT DLYGNCTLRH SGTSAAAPEA AGVFALALEA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PCSK2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PCSK2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 638 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PCSK2

Target: PCSK2 (Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2))

Andere Bezeichnung: PCSK2 (PCSK2 Produkte)

Synonyme: NEC 2 antikoerper, NEC-2 antikoerper, NEC2 antikoerper, PC2 antikoerper, SPC2 antikoerper, PCSK2 antikoerper, 6330411F23Rik antikoerper, AI839700 antikoerper, Nec-2 antikoerper, Nec2 antikoerper, Phpp-2 antikoerper, pc2 antikoerper, nec2 antikoerper, spc2 antikoerper, pcsk2 antikoerper, pcsk2-A antikoerper, proprotein convertase subtilisin/kexin type 2 antikoerper, proprotein convertase subtilisin/kexin type 2 L homeolog antikoerper, PCSK2 antikoerper, pcsk2 antikoerper, Pcsk2 antikoerper, pcsk2.L antikoerper

Hintergrund: This gene encodes a member of the subtilisin-like proprotein convertase family. These enzymes process latent precursor proteins into their biologically active products. The encoded protein plays a critical role in hormone biosynthesis by processing a variety of prohormones including proinsulin, proopiomelanocortin and proluteinizing-hormone-releasing hormone. Single nucleotide polymorphisms in this gene may increase susceptibility to myocardial infarction and type 2 diabetes. This gene may also play a role in tumor development and progression. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Alias Symbols: NEC2, PC2, SPC2, NEC 2, NEC-2
Protein Interaction Partner: PMCH, SCG5, IAPP, THRA,
Protein Size: 638

Molekulargewicht: 58 kDa

Gen-ID: 5126

NCBI Accession: NM_002594, NP_002585

UniProt: Q5REC2

Pathways: Peptide Hormone Metabolism, cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity