TNFSF4 Antikörper (Middle Region)

Produktnummer ABIN2787931

Produktdetails anti-TNFSF4 Antikörper

Target: TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNFSF4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: QEVNISLHYQ KDEEPLFQLK KVRSVNSLMV ASLTYKDKVY LNVTTDNTSL

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TNFSF4. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TNFSF4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 183 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TNFSF4

Target: TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))

Andere Bezeichnung: TNFSF4 (TNFSF4 Produkte)

Synonyme: TNFSF4 antikoerper, OX40L antikoerper, TNFRSF4 antikoerper, CD134L antikoerper, CD252 antikoerper, GP34 antikoerper, OX-40L antikoerper, OX4OL antikoerper, TXGP1 antikoerper, Ath-1 antikoerper, Ath1 antikoerper, Ox40l antikoerper, Txgp1l antikoerper, gp34 antikoerper, TNF superfamily member 4 antikoerper, tumor necrosis factor (ligand) superfamily, member 4 antikoerper, TNFSF4 antikoerper, Tnfsf4 antikoerper

Hintergrund: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF4/OX4. It is found to be involved in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD40-stimulated B cells, this cytokine along with CD70 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells.
Alias Symbols: CD134L, CD252, GP34, OX-40L, OX4OL, TXGP1
Protein Interaction Partner: TRAF2, TNFRSF4,
Protein Size: 183

Molekulargewicht: 21 kDa

Gen-ID: 7292

NCBI Accession: NM_003326, NP_003317

UniProt: P23510

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation, Cancer Immune Checkpoints