Caspase 10 Antikörper (C-Term)

Produktnummer ABIN2156524

Produktdetails anti-Caspase 10 Antikörper

Target: Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Caspase 10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: QSLCNHLKKL VPRHEDILSI LTAVNDDVSR RVDKQGTKKQ MPQPAFTLRK

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CASP10. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the c-terminal region of Human CASP10

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Caspase 10

Target: Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))

Andere Bezeichnung: CASP10 (CASP10 Produkte)

Synonyme: xCaspase-10 antikoerper, alps2 antikoerper, caspace-10 antikoerper, caspase-10 antikoerper, flice2 antikoerper, mch4 antikoerper, xCaspace-10 antikoerper, ALPS2 antikoerper, FLICE2 antikoerper, MCH4 antikoerper, caspase 10 S homeolog antikoerper, caspase 10 antikoerper, caspase-10 antikoerper, casp10.S antikoerper, casp10 antikoerper, CASP10 antikoerper, Casp10 antikoerper, LOC100848685 antikoerper

Hintergrund: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer.
Alias Symbols: ALPS2, FLICE2, MCH4
Protein Interaction Partner: FADD, PRDX6, XIAP, RB1, Dlg4, PHF20L1, OIP5, ECE2, RIOK3, NFKBIL1, CASP8, RNF34, BFAR, CASP8AP2, MSN2, PTC2, AIM9, GLN3, SLT2, GPA1, STE20, ATG13, RPL21B, VPS30, CUP9, TPK2, GAL4, FAR11, WHI3, ATG4, FAR3, FAR8, ITT1, MPH1, SSM4, ASG1, BFR1, ORT1, MBR1, CW
Protein Size: 522

Molekulargewicht: 57 kDa

Gen-ID: 843

NCBI Accession: NM_032977, NP_116759

Pathways: Apoptose, Caspase Kaskade in der Apoptose