SMARCD3 Antikörper (C-Term)
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- Target Alle SMARCD3 Antikörper anzeigen
- SMARCD3 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily D, Member 3 (SMARCD3))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SMARCD3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- DLKVMTDVAG NPEEERRAEF YHQPWSQEAV SRYFYCKIQQ RRQELEQSLV
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against Smarcd3. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product SMARCD3 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 483 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- SMARCD3 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily D, Member 3 (SMARCD3))
- Andere Bezeichnung
- Smarcd3 (SMARCD3 Produkte)
- Synonyme
- SMARCD3 antikoerper, baf60c antikoerper, cracd3 antikoerper, rsc6p antikoerper, BAF60C antikoerper, CRACD3 antikoerper, Rsc6p antikoerper, 1500001J14Rik antikoerper, 2210409C08Rik antikoerper, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 antikoerper, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 S homeolog antikoerper, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3b antikoerper, SMARCD3 antikoerper, smarcd3.S antikoerper, Smarcd3 antikoerper, smarcd3b antikoerper
- Hintergrund
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Smarcd3 plays a role in ATP dependent nucleosome remodeling by SMARCA4 containing complexes. It stimulates nuclear receptor mediated transcription. It belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth.
Alias Symbols: 1500001J14Rik, 2210409C08Rik, BAF60C
Protein Interaction Partner: Ikzf1, Smad4, Smad1, Gata4, Smarca2, Smarca4, Rbpj, Notch1,
Protein Size: 483 - Molekulargewicht
- 55 kDa
- Gen-ID
- 66993
- NCBI Accession
- NM_025891, NP_080167
- UniProt
- Q6P9Z1
- Pathways
- Regulation of Lipid Metabolism by PPARalpha
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