GTF2I Antikörper (Middle Region)

Produktnummer ABIN2787508

Produktdetails anti-GTF2I Antikörper

Target: GTF2I (General Transcription Factor III (GTF2I))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Rind (Kuh), Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GTF2I Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: INNQLVDQSE SEGPVIQESA EPSQLEVPAT EEIKETDGSS QIKQEPDPTW

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against GTF2I. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GTF2I

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 998 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-GTF2I Antikörper (ABIN2787508)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Details zu GTF2I

Target: GTF2I (General Transcription Factor III (GTF2I))

Andere Bezeichnung: GTF2I (GTF2I Produkte)

Synonyme: BAP135 antikoerper, BTKAP1 antikoerper, DIWS antikoerper, GTFII-I antikoerper, IB291 antikoerper, SPIN antikoerper, TFII-I antikoerper, WBS antikoerper, WBSCR6 antikoerper, Gtf2ird1 antikoerper, 6030441I21Rik antikoerper, BAP-135 antikoerper, GtfII-I antikoerper, Spin antikoerper, bap-135 antikoerper, bap135 antikoerper, btkap1 antikoerper, diws antikoerper, gtfii-i antikoerper, ib291 antikoerper, spin antikoerper, tfii-i antikoerper, wbs antikoerper, wbscr6 antikoerper, gtf2i antikoerper, gtf2i.L antikoerper, general transcription factor IIi antikoerper, general transcription factor II I antikoerper, general transcription factor IIi S homeolog antikoerper, GTF2I antikoerper, Gtf2i antikoerper, gtf2i antikoerper, gtf2i.S antikoerper

Hintergrund: GTF2I is a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23.This gene encodes a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. The exon(s) encoding 5' UTR has not been fully defined, but this gene is known to contain at least 34 exons, and its alternative splicing generates 4 transcript variants. This gene encodes a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. Four transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: BAP-135, BAP135, BTKAP1, DIWS, IB291, SPIN, TFII-I, WBS, WBSCR6, GTFII-I
Protein Interaction Partner: TP53, ZMYM3, PIAS2, TUBG1, TRAF6, SUMO2, SUMO3, AP2B1, DPY30, GCC1, MTUS2, MDM2, UBC, SUMO1, RPA3, RPA2, RPA1, EED, RNF2, SUZ12, CTPS2, WARS, RPL28, RAD23B, PRPS2, PRKDC, NUCB1, METTL1, ADSL, FBXO6, UBD, CBX2, TAB2, AP4S1, CBX4, MAPK12, C4BPA, MAP3K3, SLU
Protein Size: 998

Molekulargewicht: 112 kDa

Gen-ID: 2969

NCBI Accession: NM_032999, NP_127492

UniProt: P78347