GTF2I Antikörper (N-Term)

Produktnummer ABIN2777491

Produktdetails anti-GTF2I Antikörper

Target: GTF2I (General Transcription Factor III (GTF2I))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Rind (Kuh), Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GTF2I Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: ILSPGGSCGP IKVKTEPTED SGISLEMAAV TVKEESEDPD YYQYNIQGSH

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against GTF2I. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GTF2I

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 978 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GTF2I

Target: GTF2I (General Transcription Factor III (GTF2I))

Andere Bezeichnung: GTF2I (GTF2I Produkte)

Synonyme: BAP135 antikoerper, BTKAP1 antikoerper, DIWS antikoerper, GTFII-I antikoerper, IB291 antikoerper, SPIN antikoerper, TFII-I antikoerper, WBS antikoerper, WBSCR6 antikoerper, Gtf2ird1 antikoerper, 6030441I21Rik antikoerper, BAP-135 antikoerper, GtfII-I antikoerper, Spin antikoerper, bap-135 antikoerper, bap135 antikoerper, btkap1 antikoerper, diws antikoerper, gtfii-i antikoerper, ib291 antikoerper, spin antikoerper, tfii-i antikoerper, wbs antikoerper, wbscr6 antikoerper, gtf2i antikoerper, gtf2i.L antikoerper, general transcription factor IIi antikoerper, general transcription factor II I antikoerper, general transcription factor IIi S homeolog antikoerper, GTF2I antikoerper, Gtf2i antikoerper, gtf2i antikoerper, gtf2i.S antikoerper

Hintergrund: GTF2I encodes a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. The exon(s) encoding 5' UTR has not been fully defined, but this gene is known to contain at least 34 exons, and its alternative splicing generates 4 transcript variants.
Alias Symbols: WBS, DIWS, SPIN, IB291, BAP135, BTKAP1, TFII-I, WBSCR6, GTFII-I
Protein Interaction Partner: TP53, ZMYM3, PIAS2, TUBG1, TRAF6, SUMO2, SUMO3, AP2B1, DPY30, GCC1, MTUS2, MDM2, UBC, SUMO1, RPA3, RPA2, RPA1, EED, RNF2, SUZ12, CTPS2, WARS, RPL28, RAD23B, PRPS2, PRKDC, NUCB1, METTL1, ADSL, FBXO6, UBD, CBX2, TAB2, AP4S1, CBX4, MAPK12, C4BPA, MAP3K3, SLU
Protein Size: 978

Molekulargewicht: 110 kDa

Gen-ID: 2969

NCBI Accession: NM_033000, NP_127493

UniProt: Q75M86