RALB Antikörper (Middle Region)

Produktnummer ABIN2786741

Produktdetails anti-RALB Antikörper

Target: RALB (Ralb) (V-Ral Simian Leukemia Viral Oncogene Homolog B (Ras Related, GTP Binding Protein) (Ralb))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Zebrafisch (Danio rerio), Ziege, Meerschweinchen, Pferd, Kaninchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RALB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: EHESFTATAE FREQILRVKS EEDKIPLLVV GNKSDLEERR QVPVDEARGK

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Ralb. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Mouse Ralb

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 206 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RALB

Target: RALB (Ralb) (V-Ral Simian Leukemia Viral Oncogene Homolog B (Ras Related, GTP Binding Protein) (Ralb))

Andere Bezeichnung: Ralb (Ralb Produkte)

Synonyme: dRalb antikoerper, 5730472O18Rik antikoerper, Ral B antikoerper, ralb antikoerper, xralb antikoerper, zgc:100801 antikoerper, KRAS2 antikoerper, k-ras antikoerper, RAS like proto-oncogene B antikoerper, v-ral simian leukemia viral oncogene B antikoerper, v-ral simian leukemia viral oncogene homolog B L homeolog antikoerper, v-ral simian leukemia viral oncogene homolog Ba (ras related) antikoerper, v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) antikoerper, RALB antikoerper, Ralb antikoerper, ralb.L antikoerper, ralba antikoerper, ralb antikoerper

Hintergrund: Ralb is a multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Ralb accomplishes its multiple functions by interacting with distinct downstream effectors. It acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. It is required both to stabilize the assembly of the exocyst complex and to localize functional exocyst complexes to the leading edge of migrating cells. Ralb plays a role in the late stages of cytokinesis and is required for the abscission of the bridge joining the sister cells emerging from mitosis. It is required for suppression of apoptosis.
Alias Symbols: 5730472O18Rik
Protein Interaction Partner: Rgl3,
Protein Size: 206

Molekulargewicht: 23 kDa

Gen-ID: 64143

NCBI Accession: NM_022327, NP_071722

UniProt: Q9JIW9

Pathways: Neurotrophin Signalübertragung, CXCR4-mediated Signaling Events