RALB Antikörper (C-Term)

Produktnummer ABIN6264625

Produktdetails anti-RALB Antikörper

Target: RALB (Ralb) (V-Ral Simian Leukemia Viral Oncogene Homolog B (Ras Related, GTP Binding Protein) (Ralb))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RALB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: RALB Antibody detects endogenous levels of total RALB.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human RALB, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu RALB

Target: RALB (Ralb) (V-Ral Simian Leukemia Viral Oncogene Homolog B (Ras Related, GTP Binding Protein) (Ralb))

Andere Bezeichnung: RALB (Ralb Produkte)

Synonyme: dRalb antikoerper, 5730472O18Rik antikoerper, Ral B antikoerper, ralb antikoerper, xralb antikoerper, zgc:100801 antikoerper, KRAS2 antikoerper, k-ras antikoerper, RAS like proto-oncogene B antikoerper, v-ral simian leukemia viral oncogene B antikoerper, v-ral simian leukemia viral oncogene homolog B L homeolog antikoerper, v-ral simian leukemia viral oncogene homolog Ba (ras related) antikoerper, v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) antikoerper, RALB antikoerper, Ralb antikoerper, ralb.L antikoerper, ralba antikoerper, ralb antikoerper

Hintergrund:

Description: Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles (By similarity). Required both to stabilize the assembly of the exocyst complex and to localize functional exocyst complexes to the leading edge of migrating cells (By similarity). Required for suppression of apoptosis (PubMed:17875936). In late stages of cytokinesis, upon completion of the bridge formation between dividing cells, mediates exocyst recruitment to the midbody to drive abscission (PubMed:18756269).

Gene: RALB

Molekulargewicht: 23 kDa

Gen-ID: 5899

UniProt: P11234

Pathways: Neurotrophin Signalübertragung, CXCR4-mediated Signaling Events