RPSA/Laminin Receptor Antikörper (N-Term)

Produktnummer ABIN785703

Produktdetails anti-RPSA/Laminin Receptor Antikörper

Target: RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schaf, Schwein, Hund, Ziege, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RPSA/Laminin Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: QMKEEDVLKF LAAGTHLGGT NLDFQMEQYI YKRKSDGIYI INLKRTWEKL

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against Rpsa. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 295 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RPSA/Laminin Receptor

Target: RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))

Andere Bezeichnung: Rpsa (RPSA Produkte)

Synonyme: 37LRP antikoerper, 67LR antikoerper, LBP/p40 antikoerper, LRP/LR antikoerper, LamR antikoerper, rpsa antikoerper, LamR1 antikoerper, RPSA antikoerper, LAMBR antikoerper, LAMR1 antikoerper, LBP antikoerper, LRP antikoerper, NEM/1CHD4 antikoerper, SA antikoerper, lamR antikoerper, p40 antikoerper, 67kDa antikoerper, 67lr antikoerper, AL022858 antikoerper, Lamr antikoerper, Lamr1 antikoerper, Lamrl1 antikoerper, MLR antikoerper, P40 antikoerper, P40-3 antikoerper, P40-8 antikoerper, lamr1 antikoerper, zgc:55831 antikoerper, zgc:77824 antikoerper, DMRT1 antikoerper, 40S ribosomal protein SA antikoerper, 67kD laminin receptor antikoerper, ribosomal protein SA antikoerper, rssa antikoerper, rpsa antikoerper, RPSA antikoerper, Rpsa antikoerper, LOC100144340 antikoerper

Hintergrund: Rpsa is required for the assembly and/or stability of the 40S ribosomal subunit. It is also required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. It slso functions as a cell surface receptor for laminin. It plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. It may play a role in cell fate determination and tissue morphogenesis. It also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria. It enables malignant tumor cells to penetrate laminin tissue and vessel barriers and activates precursor thymic anti-OFA/iLRP specific cytotoxic T cell. It may induce CD8 T-suppressor cells secreting IL-10.
Alias Symbols: 67 kDa, 67lr, AL022858, Lamr, Lamr1, Lamrl1, MGC117921, MGC118614, MLR, P40, P40-3, P40-8
Protein Interaction Partner: Eed, Rara, Rpgrip1l, Tcf3,
Protein Size: 295

Molekulargewicht: 32 kDa

Gen-ID: 16785

NCBI Accession: NM_011029, NP_035159

UniProt: P14206

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly