PACS2 Antikörper (Middle Region)

Produktnummer ABIN2784562

Produktdetails anti-PACS2 Antikörper

Target: PACS2 (phosphofurin Acidic Cluster Sorting Protein 2 (PACS2))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PACS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: AHQLPIAEAM LTYKQKSPDE ESSQKFIPFV GVVKVGIVEP SSATSGDSDD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against PACS2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PACS2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 889 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PACS2

Target: PACS2 (phosphofurin Acidic Cluster Sorting Protein 2 (PACS2))

Andere Bezeichnung: PACS2 (PACS2 Produkte)

Synonyme: PACS-2 antikoerper, PACS1L antikoerper, 6720425G15Rik antikoerper, AW208651 antikoerper, AW489976 antikoerper, E230011J22 antikoerper, Pacs1l antikoerper, mKIAA0602 antikoerper, phosphofurin acidic cluster sorting protein 2 antikoerper, PACS2 antikoerper, Pacs2 antikoerper

Hintergrund: PACS2 is the multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptic inducer,PACS2 translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death.PACS2 may also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments.
Alias Symbols: FLJ25488, KIAA0602, PACS1L, PACS-2
Protein Interaction Partner: UBC, TRAF2, BIRC3, BIRC2, PKD2, BID,
Protein Size: 889

Molekulargewicht: 98 kDa

Gen-ID: 23241

NCBI Accession: NM_015197, NP_056012

UniProt: Q86VP3