CYP2R1 Antikörper (Middle Region)

Produktnummer ABIN2783924

Produktdetails anti-CYP2R1 Antikörper

Target: CYP2R1 (Cytochrome P450, Family 2, Subfamily R, Polypeptide 1 (CYP2R1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Schwein, Hund, Pferd, Rind (Kuh), Kaninchen, Zebrafisch (Danio rerio), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYP2R1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: FKQLITNAVS NITNLIIFGE RFTYEDTDFQ HMIELFSENV ELAASASVFL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against CYP2R1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CYP2R1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 501 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CYP2R1

Target: CYP2R1 (Cytochrome P450, Family 2, Subfamily R, Polypeptide 1 (CYP2R1))

Andere Bezeichnung: CYP2R1 (CYP2R1 Produkte)

Synonyme: cytochrome P450 family 2 subfamily R member 1 antikoerper, cytochrome P450, family 2, subfamily R, polypeptide 1 antikoerper, cytochrome P450, family 2, subfamily r, polypeptide 1 antikoerper, CYP2R1 antikoerper, cyp2r1 antikoerper, Cyp2r1 antikoerper

Hintergrund: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in this gene has been associated with selective 25-hydroxyvitamin D deficiency.
Alias Symbols: MGC4663
Protein Size: 501

Molekulargewicht: 57 kDa

Gen-ID: 120227

NCBI Accession: NM_024514, NP_078790

UniProt: Q6VVX0

Pathways: Metabolism of Steroid Hormones and Vitamin D