CYP2R1 Antikörper (AA 252-501)

Produktnummer ABIN6139341

Produktdetails anti-CYP2R1 Antikörper

Target: CYP2R1 (Cytochrome P450, Family 2, Subfamily R, Polypeptide 1 (CYP2R1))

Bindungsspezifität: AA 252-501

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYP2R1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: VVYDFLSRLI EKASVNRKPQ LPQHFVDAYL DEMDQGKNDP SSTFSKENLI FSVGELIIAG TETTTNVLRW AILFMALYPN IQGQVQKEID LIMGPNGKPS WDDKCKMPYT EAVLHEVLRF CNIVPLGIFH ATSEDAVVRG YSIPKGTTVI TNLYSVHFDE KYWRDPEVFH PERFLDSSGY FAKKEALVPF SLGRRHCLGE HLARMEMFLF FTALLQRFHL HFPHELVPDL KPRLGMTLQP QPYLICAERR

Kreuzreaktivität: Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 252-501 of human CYP2R1 (NP_078790.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CYP2R1

Target: CYP2R1 (Cytochrome P450, Family 2, Subfamily R, Polypeptide 1 (CYP2R1))

Andere Bezeichnung: CYP2R1 (CYP2R1 Produkte)

Synonyme: cytochrome P450 family 2 subfamily R member 1 antikoerper, cytochrome P450, family 2, subfamily R, polypeptide 1 antikoerper, cytochrome P450, family 2, subfamily r, polypeptide 1 antikoerper, CYP2R1 antikoerper, cyp2r1 antikoerper, Cyp2r1 antikoerper

Hintergrund: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in this gene has been associated with selective 25-hydroxyvitamin D deficiency.,CYP2R1,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Mitochondrial metabolism,Cytochromes,Lipid Metabolism,Cytochromes,Lipases,Drug metabolism,Cardiovascular,Lipids,CYP2R1

Molekulargewicht: 57 kDa

Gen-ID: 120227

UniProt: Q6VVX0

Pathways: Metabolism of Steroid Hormones and Vitamin D