HLA-DQA2 Antikörper (Middle Region)
-
- Target Alle HLA-DQA2 Antikörper anzeigen
- HLA-DQA2 (Major Histocompatibility Complex, Class II, DQ alpha 2 (HLA-DQA2))
-
Bindungsspezifität
- Middle Region
- Reaktivität
- Human, Maus, Schaf, Rind (Kuh), Ziege, Kaninchen, Pferd, Schwein
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser HLA-DQA2 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB)
- Sequenz
- LPMFSKFISF DPQSALRNMA VGKHTLEFMM RQSNSTAATN EVPEVTVFSK
- Homologie
- Cow: 86%, Goat: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 86%, Sheep: 86%
- Produktmerkmale
- This is a rabbit polyclonal antibody against HLA-DQA2. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human HLA-DQA2
- Top Product
- Discover our top product HLA-DQA2 Primärantikörper
-
-
- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
-
Antigen size: 255 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- HLA-DQA2 (Major Histocompatibility Complex, Class II, DQ alpha 2 (HLA-DQA2))
- Andere Bezeichnung
- HLA-DQA2 (HLA-DQA2 Produkte)
- Synonyme
- DX-ALPHA antikoerper, HLA-DXA antikoerper, major histocompatibility complex, class II, DQ alpha 2 antikoerper, HLA-DQA2 antikoerper
- Hintergrund
-
This gene belongs to the HLA class II alpha chain family. The encoded protein forms a heterodimer with a class II beta chain. It is located in intracellular vesicles and plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (B lymphocytes, dendritic cells, macrophages) and are used to present antigenic peptides on the cell surface to be recognized by CD4 T-cells.
Alias Symbols: DQ alpha, HLA-DXA, DX-ALPHA
Protein Interaction Partner: UBC, HLA-DQB1, CD4, INS,
Protein Size: 255 - Molekulargewicht
- 28 kDa
- Gen-ID
- 3118
- NCBI Accession
- NM_020056, NP_064440
- UniProt
- P01906
- Pathways
- T-Zell Rezeptor Signalweg
-