HLA-DQA2 Antikörper (N-Term)

Produktnummer ABIN785441

Produktdetails anti-HLA-DQA2 Antikörper

Target: HLA-DQA2 (Major Histocompatibility Complex, Class II, DQ alpha 2 (HLA-DQA2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Schaf, Rind (Kuh), Ziege, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HLA-DQA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GVNFYQSHGP SGQYTHEFDG DEEFYVDLET KETVWQLPMF SKFISFDPQS

Homologie: Cow: 100%, Goat: 100%, Human: 100%, Mouse: 85%, Rabbit: 86%, Rat: 86%, Sheep: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against HLA-DQA2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HLA-DQA2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 255 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu HLA-DQA2

Target: HLA-DQA2 (Major Histocompatibility Complex, Class II, DQ alpha 2 (HLA-DQA2))

Andere Bezeichnung: HLA-DQA2 (HLA-DQA2 Produkte)

Synonyme: DX-ALPHA antikoerper, HLA-DXA antikoerper, major histocompatibility complex, class II, DQ alpha 2 antikoerper, HLA-DQA2 antikoerper

Hintergrund: This gene belongs to the HLA class II alpha chain family. The encoded protein forms a heterodimer with a class II beta chain. It is located in intracellular vesicles and plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (B lymphocytes, dendritic cells, macrophages) and are used to present antigenic peptides on the cell surface to be recognized by CD4 T-cells.
Alias Symbols: DQ alpha, HLA-DXA, DX-ALPHA
Protein Interaction Partner: UBC, HLA-DQB1, CD4, INS,
Protein Size: 255

Molekulargewicht: 28 kDa

Gen-ID: 3118

NCBI Accession: NM_020056, NP_064440

UniProt: P01906

Pathways: T-Zell Rezeptor Signalweg