NR4A1 Antikörper (Middle Region)
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- Target Alle NR4A1 Antikörper anzeigen
- NR4A1 (Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser NR4A1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- FQKCLAVGMV KEVVRTDSLK GRRGRLPSKP KQPPDASPAN LLTSLVRAHL
- Homologie
- Cow: 85%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against NR4A1. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human NR4A1
- Top Product
- Discover our top product NR4A1 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 598 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Transformation of the Radial Glia Scaffold Demarcates Two Stages of Human Cerebral Cortex Development." in: Neuron, Vol. 91, Issue 6, pp. 1219-1227, (2016) (PubMed).
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Transformation of the Radial Glia Scaffold Demarcates Two Stages of Human Cerebral Cortex Development." in: Neuron, Vol. 91, Issue 6, pp. 1219-1227, (2016) (PubMed).
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- Target
- NR4A1 (Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1))
- Andere Bezeichnung
- NR4A1 (NR4A1 Produkte)
- Synonyme
- GFRP1 antikoerper, HMR antikoerper, N10 antikoerper, NAK-1 antikoerper, NGFIB antikoerper, NP10 antikoerper, NUR77 antikoerper, TR3 antikoerper, NGFI-B antikoerper, Gfrp antikoerper, Hbr-1 antikoerper, Hbr1 antikoerper, Hmr antikoerper, TIS1 antikoerper, nur77 antikoerper, Ngfi-b antikoerper, Nur77 antikoerper, nuclear receptor subfamily 4 group A member 1 antikoerper, nuclear receptor subfamily 4, group A, member 1 antikoerper, NR4A1 antikoerper, Nr4a1 antikoerper
- Hintergrund
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NR4A1 encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Alias Symbols: GFRP1, HMR, MGC9485, N10, NAK-1, NGFIB, NP10, NUR77, TR3
Protein Interaction Partner: KRTAP10-5, KRTAP10-1, LONRF1, PGBD1, BCL2L10, CDKN2D, BCL2A1, BCL2, TUBB4A, VASP, ANKIB1, CUTA, NFKB1, SMAD3, LSS, HADHA, GLUD1, GK, CPT1A, SERPING1, ABCC6, ABCC13, SOCS4, ABCG8, DIABLO, HCVgp1, ABCA5, CHEK2, SUGT1, PRDX4, PRDX6, CHD1L, ABCB11, ARHGEF5, U
Protein Size: 598 - Molekulargewicht
- 64 kDa
- Gen-ID
- 3164
- NCBI Accession
- NM_002135, NP_002126
- UniProt
- P22736
- Pathways
- Fc-epsilon Rezeptor Signalübertragung, Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Steroid Hormone Mediated Signaling Pathway
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