Thyroperoxidase Antikörper (N-Term)

Produktnummer ABIN2500606

Produktdetails anti-Thyroperoxidase Antikörper

Target: Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Pferd, Schwein, Kaninchen, Saccharomyces cerevisiae, Hund, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Thyroperoxidase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GASNTALARW LPPVYEDGFS QPRGWNPGFL YNGFPLPPVR EVTRHVIQVS

Homologie: Dog: 93%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 86%, Rat: 100%, Yeast: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against TPO. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human TPO

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Thyroperoxidase

Target: Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))

Andere Bezeichnung: Thyroid Peroxidase (TPO Produkte)

Synonyme: MSA antikoerper, TDH2A antikoerper, TPX antikoerper, TPO antikoerper, msa antikoerper, tpx antikoerper, xtpo antikoerper, LOC100218312 antikoerper, thyroid peroxidase antikoerper, TPO antikoerper, Tpo antikoerper, tpo antikoerper, LOC100547103 antikoerper

Hintergrund: This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined.
Protein Interaction Partner: DUOX1, TXNDC11,
Protein Size: 611

Molekulargewicht: 67 kDa

Gen-ID: 7173

Pathways: Thyroid Hormone Synthesis