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Thyroperoxidase Antikörper (AA 351-450)

TPO Reaktivität: Human, Ratte WB, IF (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN668736
  • Target Alle Thyroperoxidase (TPO) Antikörper anzeigen
    Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))
    Bindungsspezifität
    • 15
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 351-450
    Reaktivität
    • 57
    • 24
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Ratte
    Wirt
    • 39
    • 26
    • 3
    Kaninchen
    Klonalität
    • 45
    • 22
    Polyklonal
    Konjugat
    • 29
    • 10
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Thyroperoxidase Antikörper ist unkonjugiert
    Applikation
    • 51
    • 29
    • 13
    • 13
    • 13
    • 7
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human, Ratte
    Homologie
    Mouse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from mouse Thyroid peroxidase
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:300-5000
    IF(IHC-P) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))
    Andere Bezeichnung
    Thyroid peroxidase (TPO Produkte)
    Synonyme
    MSA antikoerper, TDH2A antikoerper, TPX antikoerper, TPO antikoerper, msa antikoerper, tpx antikoerper, xtpo antikoerper, LOC100218312 antikoerper, thyroid peroxidase antikoerper, TPO antikoerper, Tpo antikoerper, tpo antikoerper, LOC100547103 antikoerper
    Hintergrund

    Synonyms: Thyroid peroxidase, TPO

    Background: This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011].

    Gen-ID
    22018
    UniProt
    P35419
    Pathways
    Thyroid Hormone Synthesis
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