EPOR Antikörper (N-Term)
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- Target Alle EPOR Antikörper anzeigen
- EPOR (Erythropoietin Receptor (EPOR))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Ziege
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser EPOR Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- DHLGASLWPQ VGSLCLLLAG AAWAPPPNLP DPKFESKAAL LAARGPEELL
- Homologie
- Cow: 85%, Dog: 100%, Goat: 91%, Guinea Pig: 93%, Horse: 92%, Human: 100%, Mouse: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against EPOR. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human EPOR
- Top Product
- Discover our top product EPOR Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 508 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- EPOR (Erythropoietin Receptor (EPOR))
- Andere Bezeichnung
- EPOR (EPOR Produkte)
- Synonyme
- EPOR antikoerper, epor antikoerper, EPO-R antikoerper, erythropoietin receptor antikoerper, erythropoietin receptor L homeolog antikoerper, EPOR antikoerper, epor antikoerper, Epor antikoerper, epor.L antikoerper
- Hintergrund
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The erythropoietin receptor is a member of the cytokine receptor family. Upon erythropoietin binding, the erythropoietin receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis.The erythropoietin receptor is a member of the cytokine receptor family. Upon erythropoietin binding, the erythropoietin receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC138358, EPO-R
Protein Interaction Partner: PIK3R1, SRC, MST1R, JAK2, SH2B2, STAT5A, CBL, CRKL, GRB2, UBC, SOCS2, PLCG1, INPP5D, CISH, NOSIP, ATXN2L, GAB2, GAB1, GRAP, STAT5B, SOCS3, MAPK3, IRS2, SHC1, PLCG2, SYK, KITLG, GNB2L1, MAPK1, PTPN6, PTPN11, KLK3, LYN, KIT, VAV1, GNAI1, CSF2RB, EPOR, EPO,
Protein Size: 508 - Molekulargewicht
- 53 kDa
- Gen-ID
- 2057
- NCBI Accession
- NM_000121, NP_000112
- UniProt
- P19235
- Pathways
- JAK-STAT Signalweg
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