SLC11A2 Antikörper (N-Term)

Produktnummer ABIN2781546

Produktdetails anti-SLC11A2 Antikörper

Target: SLC11A2 (Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 2 (SLC11A2))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC11A2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: VLGPEQKMSD DSVSGDHGES ASLGNINPAY SNPSLSQSPG DSEEYFATYF

Spezifität: Specific to all four isoforms of the SLC11A2 transporter.

Homologie: Human: 100%, Rat: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against SLC11A2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SLC11A2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 561 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SLC11A2

Target: SLC11A2 (Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 2 (SLC11A2))

Andere Bezeichnung: SLC11A2 (SLC11A2 Produkte)

Synonyme: DCT1 antikoerper, DMT1 antikoerper, NRAMP2 antikoerper, Nramp2 antikoerper, mk antikoerper, van antikoerper, Dmt1 antikoerper, ATNRAMP2 antikoerper, F8G22.4 antikoerper, F8G22_4 antikoerper, NRAMP metal ion transporter 2 antikoerper, dct1 antikoerper, dmt1 antikoerper, nramp2 antikoerper, SLC11A2 antikoerper, cb426 antikoerper, fa07b10 antikoerper, wu:fa07b10 antikoerper, zgc:136699 antikoerper, solute carrier family 11 member 2 antikoerper, solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 antikoerper, NRAMP metal ion transporter 2 antikoerper, manganese transport protein antikoerper, metal transporter Nramp2 antikoerper, solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 antikoerper, SLC11A2 antikoerper, Slc11a2 antikoerper, NRAMP2 antikoerper, LOC9327403 antikoerper, slc11a2 antikoerper

Hintergrund: The SLC11A2 is a divalent metal transporter (DMT1), which carries iron, manganese, cobalt, nickel, cadmium, lead, copper, and zinc. DMT1 participates in cellular iron absorption at the luminal surface of the duodenum as well as in other areas of the body.The SLC11A2 gene encodes a divalent metal transporter (DMT1), which carries iron, manganese, cobalt, nickel, cadmium, lead, copper, and zinc. DMT1 participates in cellular iron absorption at the luminal surface of the duodenum as well as in other areas of the body (Hubert and Hentze, 2002 [PubMed 12209011], Ludwiczek et al., 2007 [PubMed 17293870]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DCT1, DMT1, FLJ37416, NRAMP2
Protein Interaction Partner: NDFIP1, UBC, NEDD4, PARK2, NDFIP2,
Protein Size: 561

Molekulargewicht: 61 kDa

Gen-ID: 4891

NCBI Accession: NM_000617, NP_000608

UniProt: P49281

Pathways: Transition Metal Ion Homeostasis, Proton Transport, Positive Regulation of Endopeptidase Activity