SLC11A1 Antikörper (Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 1) (C-Term)

Details for Product anti-SLC11A1 Antibody No. ABIN2781545, Anbieter: Anmelden zum Anzeigen
Antigen
  • SLC11A1
  • NRAMP1
  • LSH
  • NRAMP
  • Bcg
  • Itg
  • Lsh
  • Nramp1
  • Ity
  • Nramp
  • ity
  • BCG
  • solute carrier family 11 member 1 L homeolog
  • solute carrier family 11 member 1
  • solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
  • slc11a1.L
  • SLC11A1
  • Slc11a1
Epitop
C-Term
9
7
4
4
3
2
2
2
2
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Schaf
48
5
3
2
2
2
2
1
1
1
1
Wirt
Kaninchen
30
21
Klonalität
Polyklonal
Konjugat
Dieser SLC11A1 Antikörper ist unkonjugiert
2
2
2
2
2
2
2
2
1
1
1
1
1
Applikation
Western Blotting (WB)
34
17
14
4
4
1
1
1
1
1
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human SLC11A1
Sequenz VLLTRSCAIL PTVLVAVFRD LRDLSGLNDL LNVLQSLLLP FAVLPILTFT
Homologie Cow: 100%, Dog: 93%, Goat: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Sheep: 93%
Produktmerkmale This is a rabbit polyclonal antibody against SLC11A1. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Protein A purified
Andere Bezeichnung SLC11A1 (SLC11A1 Antibody Abstract)
Hintergrund SLC11A1 is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family and is a multi-pass membrane protein. The protein functions as a divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in its gene have been associated with susceptibility to infectious diseases such as tuberculosis and leprosy, and inflammatory diseases such as rheumatoid arthritis and Crohn disease.
Alias Symbols: LSH, NRAMP, NRAMP1
Protein Size: 550
Molekulargewicht 61 kDa
Gen-ID 6556
NCBI Accession NM_000578, NP_000569
UniProt P49279
Pathways Transition Metal Ion Homeostasis, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 550 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Western Blotting (WB) image for anti-Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 1 (SLC11A1) (C-Term) antibody (ABIN2781545) WB Suggested Anti-SLC11A1 Antibody Titration: 1.25ug/ml
Positive Control...
Produkt verwendet in: Usuda, Kono, Hayashi, Kawasaki, Mitsui, Shibutani, Dote, Adachi, Fujihara, Shimbo, Sun, Lu, Nakasuji: "Determination of reference concentrations of strontium in urine by inductively coupled plasma atomic emission spectrometry." in: Environmental health and preventive medicine, Vol. 11, Issue 1, pp. 11-6, 2011 (PubMed).

Allgemeine Veröffentlichungen Awomoyi, Sirugo, Newport, Tishkoff: "Global distribution of a novel trinucleotide microsatellite polymorphism (ATA)n in intron 8 of the SLC11A1 gene and susceptibility to pulmonary tuberculosis." in: International journal of immunogenetics, Vol. 33, Issue 1, pp. 11-5, 2006 (PubMed).

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