SCN3B Antikörper (N-Term)

Produktnummer ABIN2780215

Produktdetails anti-SCN3B Antikörper

Target: SCN3B (Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B))

Bindungsspezifität: N-Term

Reaktivität: Ratte, Human, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SCN3B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RPEGGKDFLI YEYRNGHQEV ESPFQGRLQW NGSKDLQDVS ITVLNVTLND

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SCN3B. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SCN3B

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 215 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-SCN3B Antikörper (ABIN2780215)

Ho, Zhao, Malinowski, Chahine, OLeary: "Differential expression of sodium channel ? subunits in dorsal root ganglion sensory neurons." in: The Journal of biological chemistry, Vol. 287, Issue 18, pp. 15044-53, (2012) (PubMed).

Hu, Barajas-Martinez, Burashnikov, Springer, Wu, Varro, Pfeiffer, Koopmann, Cordeiro, Guerchicoff, Pollevick, Antzelevitch: "A mutation in the beta 3 subunit of the cardiac sodium channel associated with Brugada ECG phenotype." in: Circulation. Cardiovascular genetics, Vol. 2, Issue 3, pp. 270-8, (2009) (PubMed).

Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

Details zu SCN3B

Target: SCN3B (Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B))

Andere Bezeichnung: SCN3B (SCN3B Produkte)

Synonyme: 1110001K16Rik antikoerper, 4833414B02Rik antikoerper, Scnb3 antikoerper, HSA243396 antikoerper, SCNB3 antikoerper, sodium voltage-gated channel beta subunit 3 antikoerper, sodium channel, voltage-gated, type III, beta antikoerper, SCN3B antikoerper, Scn3b antikoerper

Hintergrund: SCN3B is one member of the sodium channel beta subunits of voltage-gated sodium channels, which are responsible for the generation and propagation of action potentials in neurons and muscle. SCN3B influences the inactivation kinetics of the sodium channel.
Alias Symbols: HSA243396, SCNB3
Protein Interaction Partner: NFASC,
Protein Size: 215

Molekulargewicht: 24 kDa

Gen-ID: 55800

NCBI Accession: NM_018400, NP_060870

UniProt: Q9NY72