NKX3-1 Antikörper (Middle Region)

Produktnummer ABIN2779964

Produktdetails anti-NKX3-1 Antikörper

Target: NKX3-1 (NK3 Homeobox 1 (NKX3-1))

Bindungsspezifität: Middle Region

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NKX3-1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: TPTEPESDAH FETYLLDCEH NPGDLASAPQ VTKQPQKRSR AAFSHTQVIE

Homologie: Mouse: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Nkx3-1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Mouse Nkx3-1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 237 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NKX3-1

Target: NKX3-1 (NK3 Homeobox 1 (NKX3-1))

Andere Bezeichnung: Nkx3-1 (NKX3-1 Produkte)

Synonyme: Xbagpipe antikoerper, Xbap antikoerper, bagpipe antikoerper, koza antikoerper, nkx3-1 antikoerper, nkx3.1 antikoerper, si:ch211-67o1.2 antikoerper, nkx3a antikoerper, MGC53041 antikoerper, MGC97890 antikoerper, Bax antikoerper, NKX3.1 antikoerper, NKX3A antikoerper, Nkx-3.1 antikoerper, BAPX2 antikoerper, NKX3 antikoerper, NK3 homeobox 1 L homeolog antikoerper, NK3 homeobox 1 antikoerper, NK-3 transcription factor, locus 1 (Drosophila) antikoerper, nkx3-1.L antikoerper, NKX3-1 antikoerper, nkx3-1 antikoerper, Nkx3-1 antikoerper

Hintergrund: Nkx3-1 is a transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. It plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Nkx3-1 acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to suppress growth and tumorigenicity of prostate carcinoma cells and plays a role in the formation of minor salivary glands (particularly palatine and lingual glands). It is essential for appropriate differentiation and secretory function of the bulbourethral gland.
Alias Symbols: Bax, NKX3.1, NKX3A, Nkx-3.1, bagpipe
Protein Interaction Partner: Fem1b, SP2,
Protein Size: 237

Molekulargewicht: 27 kDa

Gen-ID: 18095

NCBI Accession: NM_010921, NP_035051

UniProt: P97436

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Endopeptidase Activity, Positive Regulation of Response to DNA Damage Stimulus