NKX3-1 Antikörper (AA 118-145)

Produktnummer ABIN3032013

Der Kaninchen Polyklonal anti-NKX3-1 Antikörper (ABIN3032013) detektiert spezifisch NKX3-1 in IHC, WB, ELISA und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für NKX3-1 Antikörper (AA 118-145) (ABIN3032013)

Target: NKX3-1 (NK3 Homeobox 1 (NKX3-1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NKX3-1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-NKX3-1 Antikörper

Bindungsspezifität: AA 118-145

Kreuzreaktivität (Details): Expected species reactivity: Mouse

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 118-145 from the human protein was used as the immunogen for this NKX3.1 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the NKX3.1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at 4°C for up to one month. For long term, aliquot the NKX3.1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu NKX3-1

Target: NKX3-1 (NK3 Homeobox 1 (NKX3-1))

Andere Bezeichnung: NKX3.1

Hintergrund: NKX3.1 is a transcription factor which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells. [UniProt]

UniProt: Q99801

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Endopeptidase Activity, Positive Regulation of Response to DNA Damage Stimulus