TTF1 Antikörper (N-Term)

Produktnummer ABIN2779907

Produktdetails anti-TTF1 Antikörper

Target: TTF1 (Transcription Termination Factor, RNA Polymerase I (TTF1))

Bindungsspezifität: N-Term

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TTF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RRASQTPAQE TLESEWPQKA KRKKRRREPQ TPAQETLESE WPQKAKKKKR

Homologie: Mouse: 100%, Rat: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against Ttf1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the n terminal region of mouse Ttf1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 859 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TTF1

Target: TTF1 (Transcription Termination Factor, RNA Polymerase I (TTF1))

Andere Bezeichnung: Ttf1 (TTF1 Produkte)

Synonyme: TTF-1 antikoerper, TTF-I antikoerper, AV245725 antikoerper, RGD1565673 antikoerper, transcription termination factor 1 antikoerper, transcription termination factor, RNA polymerase I antikoerper, TTF1 antikoerper, Ttf1 antikoerper

Hintergrund: Ttf1 is a multifunctional nucleolar protein that terminates ribosomal gene transcription, mediates replication fork arrest and regulates RNA polymerase I transcription on chromatin.Ttf1 plays a dual role in rDNA regulation, being involved in both activation and silencing of rDNA transcription.Ttf1 interaction with BAZ2A/TIP5 recovers DNA-binding activity.
Alias Symbols: AV245725
Protein Interaction Partner: Wwtr1, Gata6,
Protein Size: 859

Molekulargewicht: 98 kDa

Gen-ID: 22130

NCBI Accession: NM_009442, NP_033468

UniProt: Q62187

Pathways: Thyroid Hormone Synthesis, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour