OAS1 Antikörper (C-Term)
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- Target Alle OAS1 Antikörper anzeigen
- OAS1 (2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser OAS1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- EAWLNYPCFK NWDGSPVSSW ILLAESNSAD DETDDPRRYQ KYGYIGTHEY
- Homologie
- Human: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against OAS1. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product OAS1 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 400 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Higher miRNA tolerance in immortal Li-Fraumeni fibroblasts with abrogated interferon signaling pathway." in: Cancer research, Vol. 71, Issue 1, pp. 255-65, (2011) (PubMed).
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Higher miRNA tolerance in immortal Li-Fraumeni fibroblasts with abrogated interferon signaling pathway." in: Cancer research, Vol. 71, Issue 1, pp. 255-65, (2011) (PubMed).
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- Target
- OAS1 (2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))
- Andere Bezeichnung
- OAS1 (OAS1 Produkte)
- Synonyme
- OAS1 antikoerper, IFI-4 antikoerper, OIAS antikoerper, OIASI antikoerper, L3 antikoerper, Pp2a2 antikoerper, 2',5'-oligoadenylate synthetase 1 antikoerper, 2'-5'-oligoadenylate synthetase 1 antikoerper, 2'-5' oligoadenylate synthetase 1A antikoerper, protein phosphatase 2 catalytic subunit beta antikoerper, OAS1 antikoerper, Oas1a antikoerper, Ppp2cb antikoerper, Oas1 antikoerper
- Hintergrund
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OAS1 is a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. It is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. Mutations in this gene have been associated with host susceptibility to viral infection.
Alias Symbols: IFI-4, OIAS, OIASI
Protein Interaction Partner: EXOC5, TRIM27, ACTN1, PRMT6, WBSCR22, RPL30, HCVgp1,
Protein Size: 400 - Molekulargewicht
- 46 kDa
- Gen-ID
- 4938
- NCBI Accession
- NM_016816, NP_058132
- UniProt
- P00973
- Pathways
- Hepatitis C
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