OAS1 Produkte
(2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))
Kategorien
This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Mutations in this gene have been associated with host susceptibility to viral infection. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].
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Ausgewählte OAS1 Kategorien
OAS1 Antikörper
High quality antibodies with extensive validation data.
OAS1 ELISA Kits
Reliable ELISA kits for a wide range of species.
OAS1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene OAS1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (8)
Kat. Nr.
ABIN7435079
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Rat
Applikation
WB, IHC, IP, ICC
Validierungen
- (6)
Kat. Nr.
ABIN7435082
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, IHC (p)
Validierungen
- (7)
- (3)
Kat. Nr.
ABIN390164
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene OAS1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN5593383
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Pig
Analytical Method
Validierungen
Kat. Nr.
ABIN1118759
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN5651267
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene OAS1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN1313295
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7121603
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1313297
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren OAS1 Produkten
: "Pattern recognition receptor-initiated innate antiviral response in mouse adipose cells." in: Immunology and cell biology, Vol. 92, Issue 2, pp. 105-15, (2014) (PubMed).: "RIG-I-like receptors mediate innate antiviral response in mouse testis." in: Molecular endocrinology (Baltimore, Md.), Vol. 27, Issue 9, pp. 1455-67, (2013) (PubMed).
: "The association of elevated 2',5'-oligoadenylate-dependent RNase L with lung cancer correlated with deficient enzymatic activity and decreased capacity of RNase L dimerization." in: Lung cancer (Amsterdam, Netherlands), Vol. 78, Issue 1, pp. 30-8, (2012) (PubMed).
: "Higher miRNA tolerance in immortal Li-Fraumeni fibroblasts with abrogated interferon signaling pathway." in: Cancer research, Vol. 71, Issue 1, pp. 255-65, (2011) (PubMed).
: "Azithromycin induces anti-viral responses in bronchial epithelial cells." in: The European respiratory journal, Vol. 36, Issue 3, pp. 646-54, (2010) (PubMed).
: "The hepatitis C virus non-structural NS5A protein impairs both the innate and adaptive hepatic immune response in vivo." in: The Journal of biological chemistry, Vol. 284, Issue 41, pp. 28343-51, (2009) (PubMed).
: "Therapeutic gene silencing delivered by a chemically modified small interfering RNA against mutant SOD1 slows amyotrophic lateral sclerosis progression." in: The Journal of biological chemistry, Vol. 283, Issue 23, pp. 15845-52, (2008) (PubMed).
: "IFI16 in human prostate cancer." in: Molecular cancer research : MCR, Vol. 5, Issue 3, pp. 251-9, (2007) (PubMed).
: "A phylogenetically conserved RNA structure in the poliovirus open reading frame inhibits the antiviral endoribonuclease RNase L." in: Journal of virology, Vol. 81, Issue 11, pp. 5561-72, (2007) (PubMed).
: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).
Synonyme und alternative Namen zu OAS1
2',5'-oligoadenylate synthetase 1 (OAS1), 2'-5'-oligoadenylate synthetase 1 (OAS1), 2'-5' oligoadenylate synthetase 1A (Oas1a), protein phosphatase 2 catalytic subunit beta (Ppp2cb), 2'-5'-oligoadenylate synthetase 1 (Oas1), IFI-4, L3, OAS1, OIAS, OIASI, Pp2a2Bezeichner auf Proteinebene für OAS1
- 2',5'-oligoadenylate synthetase 1
- 2',5'-oligoadenylate synthetase 1, 40/46kDa
- 2'-5'-oligoadenylate synthase 1
- (2-5')oligo(A) synthase 1
- (2-5')oligo(A) synthetase 1
- 2'-5' oligoadenylate synthetase
- 2-5A synthase 1
- 2-5A synthetase 1
- p42 OAS
- 2-5-oligoadenylate synthetase 1
- 2'-5' oligoadenylate synthetase 1
- 2',5'-oligo A synthetase 1
- 2'-5' oligoadenylate synthetase 1 p48 isoform
- 2'-5' oligoadenylate synthetase 1 p52 isoform
- 2'-5'-oligoisoadenylate synthetase 1
- E18/E16
- p46/p42 OAS
- 2'-5'-oligoadenylate synthetase 1-like
- 2'-5'-oligoadenylate synthetase 1, 40/46kDa
- (2-5')oligo(A) synthase 1A
- (2-5')oligo(A) synthetase 1A
- 2'-5'-oligoadenylate synthase 1A
- 2-5A synthase 1A
- 2-5A synthetase 1A
- PP2A-beta
- protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform
- protein phosphatase 2, catalytic subunit, beta isoform
- protein phosphatase 2A catalytic alpha subunit
- protein phosphatase 2a, catalytic subunit, beta isoform
- protein phosphatase-2A-beta
- serine/threonine-protein phosphatase 2A catalytic subunit beta isoform
- LOW QUALITY PROTEIN: 2'-5'-oligoadenylate synthase 1
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