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OAS1A Produkte

(2'-5' Oligoadenylate Synthetase 1A (OAS1A))
This gene is a member of the 2'-5' oligoA synthetase family, which are clustered on chromosome 5. The encoded protein functions in the interferon-regulated OAS/RNase L system, which mediates RNA decay as part of the innate antiviral immunity pathway. The protein binds double-stranded RNA and oligomerizes ATP, which activate the single-stranded RNA cleavage enzyme RNase L. This protein mediates resistance to flaviviruses such as West Nile virus. The majority of wild mouse strains produce a functional protein and are resistant to flavivirus infection, whereas some inbred mouse strains including the strain of the reference genome, C57BL/6J, contain a premature stop codon that inactivates this gene product. [provided by RefSeq, Jul 2008].

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Ausgewählte OAS1A Kategorien

OAS1A Antikörper

High quality antibodies with extensive validation data.

OAS1A ELISA Kits

Reliable ELISA kits for a wide range of species.

OAS1A Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene OAS1A Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation IHC, ELISA, WB
Validierungen
Kat. Nr. ABIN1175792
Menge 200 μL
Datenblatt Datenblatt

Empfohlene OAS1A ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6953345
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (2)
  • (1)
Kat. Nr. ABIN6953347
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6953346
Menge 96 tests
Datenblatt Datenblatt

Empfohlene OAS1A Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3132884
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren OAS1A Produkten

Tsujiuchi, Natsume, Motomura, Kondo, Ranjit, Hachisu, Sugimura, Tomita, Takehara, Woolley, Barua, Gill, Bienemann, Yamashita, Toyokuni, Wakabayashi: "Preclinical evaluation of an O(6)-methylguanine-DNA methyltransferase-siRNA/liposome complex administered by convection-enhanced delivery to rat and porcine brains." in: American journal of translational research, Vol. 6, Issue 2, pp. 169-78, (2014) (PubMed).

Bobardt, Hopkins, Baugh, Chatterji, Hernandez, Hiscott, Sluder, Lin, Gallay: "HCV NS5A and IRF9 compete for CypA binding." in: Journal of hepatology, Vol. 58, Issue 1, pp. 16-23, (2013) (PubMed).

Heyden, Fodor: "Prevention of fatal and nonfatal ischemic heart disease by early treatment of hypertension." in: Cardiology, Vol. 72 Suppl 1, pp. 182-6, (1985) (PubMed).

Synonyme und alternative Namen zu OAS1A

2'-5' oligoadenylate synthetase 1A (Oas1a), 2'-5' oligoadenylate synthetase 1B (Oas1b), Flv, L1, L3, Mmu-L1, Oas1, Oas1g, Oias-2, Oias2, Wnv

Bezeichner auf Proteinebene für OAS1A

  • (2-5')oligo(A) synthase 1
  • (2-5')oligo(A) synthase 1A
  • (2-5')oligo(A) synthetase 1
  • 2',5'-oligoadenylate synthetase 1, 40/46kDa
  • 2'-5' oligoadenylate synthetase 1G
  • 2'-5'-oligoadenylate synthase 1
  • 2'-5'-oligoadenylate synthase 1A
  • 2'-5'-oligoadenylate synthetase 1
  • 2-5A synthase 1
  • 2-5A synthase 1A
  • 2-5A synthetase 1
  • 25 oligoadenylate synthetase
  • (2-5')oligo(A) synthetase 1A
  • 2-5A synthetase 1A
  • p42 OAS
  • (2-5')oligo(A) synthase 1B
  • (2-5')oligo(A) synthetase 1b
  • 2',5'-oligoadenylate synthetase-like 1
  • 2'-5'-oligoadenylate synthase 1B
  • 2'-5'-oligoadenylate synthase-like protein 1
  • 2'-5'-oligoadenylate synthetase-like protein 1
  • 2-5A synthase 1B
  • 2-5A synthetase 1B
  • Flavivirus resistance
  • inactive 2'-5'-oligoadenylate synthase 1B
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