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Obestatin Produkte

(Obestatin (OB))
This gene encodes ghrelin-obestatin preproprotein, which generates ghrelin and obestatin. Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor and is involved in regulating growth hormone release. Obestatin was initially reported to be an endogenous ligand for the orphan G protein-coupled receptor GPR39 and was involved in satiety and decreased food intake\; however, these findings are controversial. Recent reports show that obestatin is involved in inhibiting thirst and anxiety, improving memory, regulating sleep, affecting cell proliferation, and increasing the secretion of pancreatic juice enzymes. Alternative promoters and alternative splicing result in multiple transcript variants, some of which encode different protein isoforms and some of which do not encode a protein but may regulate the ghrelin-obestatin preproprotein expression. In addition, antisense transcripts for this gene have been identified and may also function in regulation of the ghrelin-obestatin preproprotein expression. [provided by RefSeq, Oct 2008].

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Ausgewählte Obestatin Kategorien

Obestatin Antikörper

High quality antibodies with extensive validation data.

Obestatin ELISA Kits

Reliable ELISA kits for a wide range of species.

Empfohlene Obestatin Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse
Applikation ELISA
Validierungen
  • (1)
Kat. Nr. ABIN1169352
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation ELISA, IHC
Validierungen
Kat. Nr. ABIN3180771
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation ELISA, WB
Validierungen
Kat. Nr. ABIN4902035
Menge 100 μL
Datenblatt Datenblatt

Empfohlene Obestatin ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6958291
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (2)
  • (1)
Kat. Nr. ABIN6975673
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Pig
Analytical Method Quantitative Competition ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6969040
Menge 96 tests
Datenblatt Datenblatt

Neueste Publikationen zu unseren Obestatin Produkten

Yannakoulia, Anastasiou, Zachari, Sidiropoulou, Katsaounou, Tenta: "Acute effect of smoking and smoking abstinence on energy intake and appetite-related hormones blood concentrations." in: Physiology & behavior, Vol. 184, pp. 78-82, (2018) (PubMed).

Zhang, Zhai, Zhang, Zhou, Chen: "Ghrelin and obestatin plasma levels and ghrelin/obestatin prepropeptide gene polymorphisms in small for gestational age infants." in: The Journal of international medical research, Vol. 42, Issue 6, pp. 1232-42, (2015) (PubMed).

Emami, Nazem, Hedayati: "Is association between thyroid hormones and gut peptides, ghrelin and obestatin, able to suggest new regulatory relation between the HPT axis and gut?" in: Regulatory peptides, Vol. 189, pp. 17-21, (2014) (PubMed).

Ma, Zhao, Wang, Wu, Wang, Ma, Ren, Zhang, Li, Lu, Bi, Ning, Qin: "Plasma Ghrelin Concentrations Are Negatively Correlated With Urine Albumin-to-Creatinine Ratio in Newly Diagnosed Type 2 Diabetes." in: The American journal of the medical sciences, (2014) (PubMed).

Kanat, Ayten, Ayd?n, Girgin, Cetinkaya, Ilhan, Yur, Catak: "Significance of appetite hormone ghrelin and obestatin levels in the assessment of the severity of acute pancreatitis." in: The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, Vol. 25, Issue 3, pp. 309-13, (2014) (PubMed).

Johnson, Drugan, Miller, Evans: "38" in: , Vol. 1363, Issue Nucleic acids research, pp. 28-39, (1991)

Hassouna, Zizzari, Tolle: "The ghrelin/obestatin balance in the physiological and pathological control of growth hormone secretion, body composition and food intake." in: Journal of neuroendocrinology, Vol. 22, Issue 7, pp. 793-804, (2010) (PubMed).

Sjölund, Ekman, Wierup: "Covariation of plasma ghrelin and motilin in irritable bowel syndrome." in: Peptides, Vol. 31, Issue 6, pp. 1109-12, (2010) (PubMed).

Harsch, Koebnick, Tasi, Hahn, Konturek: "Ghrelin and obestatin levels in type 2 diabetic patients with and without delayed gastric emptying." in: Digestive diseases and sciences, Vol. 54, Issue 10, pp. 2161-6, (2009) (PubMed).

Gourcerol, St-Pierre, Taché: "Lack of obestatin effects on food intake: should obestatin be renamed ghrelin-associated peptide (GAP)?" in: Regulatory peptides, Vol. 141, Issue 1-3, pp. 1-7, (2007) (PubMed).

Synonyme und alternative Namen zu Obestatin

ghrelin (Ghrl), 2210006E23Rik, Ghr, m46, MTLRP, MTLRPAP

Bezeichner auf Proteinebene für Obestatin

  • appetite-regulating hormone
  • growth hormone secretagogue
  • growth hormone-releasing peptide
  • motilin-related peptide
  • preproghrelin
  • proghrelin
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