Obestatin Antikörper

Produktnummer ABIN7862539

Der Kaninchen Polyklonal anti-Obestatin Antikörper (ABIN7862539) detektiert spezifisch Obestatin in ELISA, IHC und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für Obestatin Antikörper (ABIN7862539)

Target: Obestatin (OB)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Obestatin Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-Obestatin Antikörper

Verwendungszweck: Rabbit Anti-Ob Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of Ob

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human Ob protein at AA range: 10-50

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200,ELISA 1:10000-20000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Obestatin

Target: Obestatin (OB)

Andere Bezeichnung: Ob

Hintergrund: Leptin, Obese protein, Obesity factorLEP encodes a protein that is secreted by white adipocytes into the circulation and plays a major role in the regulation of energy homeostasis. Circulating leptin binds to the leptin receptor in the brain, which activates downstream signaling pathways that inhibit feeding and promote energy expenditure. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis, reproduction, bone formation and wound healing. Mutations inLEP and its regulatory regions cause severe obesity and morbid obesity with hypogonadism in human patients. A mutation in LEP has also been linked to type 2 diabetes mellitus development. LEP (Leptin) is a Protein Coding gene. Diseases associated with LEP include Obesity, Morbid, Due To Leptin Deficiency and Obesity Due To Congenital Leptin Deficiency. Among its related pathways are Common Cytokine Receptor Gamma-Chain Family Signaling Pathways and Transcription factor regulation in adipogenesis.

Gen-ID: 3952

UniProt: P41159