SSB Antikörper (Middle Region)
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- Target Alle SSB Antikörper anzeigen
- SSB (Sjogren Syndrome Antigen B (SSB))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Hund, Pferd, Kaninchen, Rind (Kuh), Meerschweinchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SSB Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- PGQKYKETDL LILFKDDYFA KKNEERKQNK VEAKLRAKQE QEAKQKLEED
- Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against SSB. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human SSB
- Top Product
- Discover our top product SSB Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 408 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- SSB (Sjogren Syndrome Antigen B (SSB))
- Andere Bezeichnung
- SSB (SSB Produkte)
- Synonyme
- LARP3 antikoerper, La antikoerper, lab1 antikoerper, larp3 antikoerper, ssb antikoerper, Mt-SSB antikoerper, MtSSB antikoerper, Ssbp1 antikoerper, SS-B antikoerper, laa-a antikoerper, ssb-a antikoerper, ssb-b antikoerper, wu:fb17f11 antikoerper, zgc:55588 antikoerper, Sjogren syndrome antigen B antikoerper, Sjogren syndrome antigen B L homeolog antikoerper, single stranded DNA binding protein 1 antikoerper, Sjogren syndrome antigen B S homeolog antikoerper, Sjogren syndrome antigen B (autoantigen La) antikoerper, SSB antikoerper, ssb.L antikoerper, SSBP1 antikoerper, Ssb antikoerper, ssb.S antikoerper, ssb antikoerper
- Hintergrund
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SSB is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU(OH) elements of newly RNA polymerase III-transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. SSB protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome and systemic lupus erythematosus.La is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU(OH) elements of newly RNA polymerase III (see MIM 606007)-transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. La protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome (MIM 270150) and systemic lupus erythematosus La is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU(OH) elements of newly RNA polymerase III (see MIM 606007)-transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. La protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome (MIM 270150) and systemic lupus erythematosus (SLE, MIM 152700) (Teplova et al., 2006 [PubMed 16387655]).[supplied by OMIM]. Sequence Note: removed 1 base from the 3' end that did not align to the reference genome assembly. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1673 BC020818.1 1-1673
Alias Symbols: LARP3, La
Protein Interaction Partner: HUWE1, UBC, MDM2, LIN28A, BMI1, SUZ12, RNF2, rev, NPLOC4, DNM1L, UBA2, ANP32A, VBP1, RABGGTA, PPP2CA, KARS, CTTN, TARDBP, SOX2, HMGA1, ARFGEF1, NCL, GZMH, CSNK2B, CSNK2A1, HCVgp1, CBX6, SPIB, IL7R, IFIT3, FN1, SMURF1, BARD1, PAXIP1, APP, TROVE2, XIAP, CAN
Protein Size: 408 - Molekulargewicht
- 47 kDa
- Gen-ID
- 6741
- NCBI Accession
- NM_003142, NP_003133
- UniProt
- P05455
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