SMARCB1 Antikörper (N-Term)

Produktnummer ABIN2778301

Produktdetails anti-SMARCB1 Antikörper

Target: SMARCB1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 (SMARCB1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMARCB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: RGSLYKRYPS LWRRLATVEE RKKIVASSHG KKTKPNTKDH GYTTLATSVT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SMARCB1. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SMARCB1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 385 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SMARCB1

Target: SMARCB1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 (SMARCB1))

Andere Bezeichnung: SMARCB1 (SMARCB1 Produkte)

Synonyme: SMARCB1 antikoerper, BAF47 antikoerper, INI1 antikoerper, MRD15 antikoerper, RDT antikoerper, RTPS1 antikoerper, SNF5 antikoerper, SNF5L1 antikoerper, Sfh1p antikoerper, Snr1 antikoerper, hSNFS antikoerper, AU020204 antikoerper, Baf47 antikoerper, Ini1 antikoerper, SNF5/INI1 antikoerper, Snf5 antikoerper, fc51b01 antikoerper, smarcb1 antikoerper, wu:fc51b01 antikoerper, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 antikoerper, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 S homeolog antikoerper, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1b antikoerper, SMARCB1 antikoerper, Smarcb1 antikoerper, smarcb1.S antikoerper, smarcb1b antikoerper

Hintergrund: The protein encoded by SMARCB1 is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. SMARCB1 has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors.
Alias Symbols: RDT, INI1, SNF5, Snr1, BAF47, RTPS1, Sfh1p, hSNFS, SNF5L1
Protein Interaction Partner: UBC, SOX2, tat, EPAS1, TRA2A, NCSTN, SAP18, EIF4A3, ARID1A, DPF1, VTN, TOP2B, SON, SMARCE1, SMARCD3, SMARCD2, SMARCD1, SMARCC2, SMARCA4, SMARCA2, SMARCC1, ARID1B, HDAC2, APP, PHF10, UBD, COPS5, CUL3, TFAP4, CAND1, RB1CC1, UBB, CEBPB, UL114, UL44, CHFR, DP
Protein Size: 385

Molekulargewicht: 44 kDa

Gen-ID: 6598

NCBI Accession: NM_003073, NP_003064

UniProt: Q12824