TH Antikörper (N-Term)

Produktnummer ABIN2777174

Produktdetails anti-TH Antikörper

Target: TH

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus, Kaninchen, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GAPGPSLTGS PWPGTAAPAA SYTPTPRSPR FIGRRQSLIE DARKEREAAV

Homologie: Cow: 91%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TH. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the n terminal region of human TH

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 528 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TH

Target: TH

Abstract: TH Produkte

Synonyme: DYT14 antikoerper, DYT5b antikoerper, TYH antikoerper, The antikoerper, tyrosine hydroxylase antikoerper, TH antikoerper, Th antikoerper

Hintergrund: The specific function of the protein remains unknown. The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Alias Symbols: TYH, DYT14, DYT5b
Protein Interaction Partner: TYSND1, YWHAQ, MAPKAPK2, CDK11B, RPS6KA5, CAMK2G, MAPK3, PRKACA, YWHAB, YWHAZ, MAPK1, SNCA, CSNK2A1,
Protein Size: 528

Molekulargewicht: 58 kDa

Gen-ID: 7054

NCBI Accession: NM_199292, NP_954986

UniProt: P07101