TH Antikörper (C-Term)

Produktnummer ABIN1881881

Produktdetails anti-TH Antikörper

Target: TH

Bindungsspezifität: AA 486-514, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Immunogen: This TH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 486-514 amino acids from the C-terminal region of human TH.

Klon: RB21096

Anwendungsinformationen

Applikationshinweise: WB: 1:1000,IHC (p): 1:50-100,FACS: 1:10-50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Referenzen für anti-TH Antikörper (ABIN1881881)

Kuhn, Sadidi, Liu, Kreipke, Geddes, Borges, Watson et al.: "Peroxynitrite-induced nitration of tyrosine hydroxylase: identification of tyrosines 423, 428, and 432 as sites of modification by matrix-assisted laser desorption ionization time-of-flight mass..." in: The Journal of biological chemistry, Vol. 277, Issue 16, pp. 14336-42, (2002) (PubMed).

Details zu TH

Target: TH

Abstract: TH Produkte

Synonyme: DYT14 antikoerper, DYT5b antikoerper, TYH antikoerper, The antikoerper, tyrosine hydroxylase antikoerper, TH antikoerper, Th antikoerper

Hintergrund: TH is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons.

Synonyms: TH, TYH, Tyrosine 3-monooxygenase, Tyrosine 3-hydroxylase

NCBI Accession: NP_954986, NP_954987, NP_000351

UniProt: P07101