PPFIBP1 Antikörper (N-Term)
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- Target Alle PPFIBP1 Antikörper anzeigen
- PPFIBP1 (PTPRF Interacting Protein, Binding Protein 1 (Liprin beta 1) (PPFIBP1))
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Bindungsspezifität
- N-Term
- Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen, Hund, Meerschweinchen, Schwein, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PPFIBP1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- PFMGSLRALH LVEDLRGLLE MMETDEKEGL RCQIPDSTAE TLVEWLQSQM
- Homologie
- Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
- Produktmerkmale
- This is a rabbit polyclonal antibody against PPFIBP1. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human PPFIBP1
- Top Product
- Discover our top product PPFIBP1 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 170 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PPFIBP1 (PTPRF Interacting Protein, Binding Protein 1 (Liprin beta 1) (PPFIBP1))
- Andere Bezeichnung
- PPFIBP1 (PPFIBP1 Produkte)
- Synonyme
- liprin-beta-1 antikoerper, L2 antikoerper, SGT2 antikoerper, hSGT2 antikoerper, hSgt2p antikoerper, 4632409B19Rik antikoerper, AW214454 antikoerper, AW261454 antikoerper, PPFIA binding protein 1 antikoerper, PTPRF interacting protein, binding protein 1 (liprin beta 1) antikoerper, PTPRF interacting protein, binding protein 1 (liprin beta 1) S homeolog antikoerper, Ppfibp1 antikoerper, ppfibp1 antikoerper, ppfibp1.S antikoerper, PPFIBP1 antikoerper
- Hintergrund
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PPFIBP1 is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis.The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alias Symbols: L2, hSGT2, hSgt2p, SGT2
Protein Interaction Partner: VCP, TP53, CDKN1A, CEP76, CEP250, LATS2, YWHAQ, YWHAB, UBC, GRK5, SH3KBP1, ELAVL1, YWHAG, S100A4, PPFIA1, PPFIA3, PPFIA2, PPFIBP1, PTPRM, SFN,
Protein Size: 170 - Molekulargewicht
- 19 kDa
- Gen-ID
- 8496
- NCBI Accession
- NM_177444, NP_803193
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