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PPFIBP1 Antikörper (AA 588-617)

PPFIBP1 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB37193 unconjugated
Produktnummer ABIN1538519
  • Target Alle PPFIBP1 Antikörper anzeigen
    PPFIBP1 (PTPRF Interacting Protein, Binding Protein 1 (Liprin beta 1) (PPFIBP1))
    Bindungsspezifität
    • 10
    • 6
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 588-617
    Reaktivität
    • 31
    • 9
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 31
    Kaninchen
    Klonalität
    • 31
    Polyklonal
    Konjugat
    • 14
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PPFIBP1 Antikörper ist unkonjugiert
    Applikation
    • 24
    • 19
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    M
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This PPFIBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 588-617 amino acids from the Central region of human PPFIBP1.
    Klon
    RB37193
    Isotyp
    Ig Fraction
  • Applikationshinweise
    WB: 1:2000. IHC-P: 1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    PPFIBP1 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    Haltbarkeit
    6 months
  • Target
    PPFIBP1 (PTPRF Interacting Protein, Binding Protein 1 (Liprin beta 1) (PPFIBP1))
    Andere Bezeichnung
    PPFIBP1 (PPFIBP1 Produkte)
    Synonyme
    liprin-beta-1 antikoerper, L2 antikoerper, SGT2 antikoerper, hSGT2 antikoerper, hSgt2p antikoerper, 4632409B19Rik antikoerper, AW214454 antikoerper, AW261454 antikoerper, PPFIA binding protein 1 antikoerper, PTPRF interacting protein, binding protein 1 (liprin beta 1) antikoerper, PTPRF interacting protein, binding protein 1 (liprin beta 1) S homeolog antikoerper, Ppfibp1 antikoerper, ppfibp1 antikoerper, ppfibp1.S antikoerper, PPFIBP1 antikoerper
    Hintergrund
    The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
    Molekulargewicht
    114024
    Gen-ID
    8496
    NCBI Accession
    NP_001185844, NP_001185845, NP_003613, NP_803193
    UniProt
    Q86W92
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