CHRNA7 Antikörper (Middle Region)
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- Target Alle CHRNA7 Antikörper anzeigen
- CHRNA7 (Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Ratte, Maus, Rind (Kuh), Hund, Pferd, Meerschweinchen, Kaninchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CHRNA7 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- VPTPDSGVVC GRMACSPTHD EHLLHGGQPP EGDPDLAKIL EEVRYIANRF
- Homologie
- Cow: 100%, Dog: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against CHRNA7. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human CHRNA7
- Top Product
- Discover our top product CHRNA7 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 502 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CHRNA7 (Cholinergic Receptor, Nicotinic, alpha 7 (Neuronal) (CHRNA7))
- Andere Bezeichnung
- CHRNA7 (CHRNA7 Produkte)
- Synonyme
- CHRNA7-2 antikoerper, NACHRA7 antikoerper, dZ70B1.1 antikoerper, Acra7 antikoerper, alpha7 antikoerper, BTX antikoerper, NARAD antikoerper, nAChRa7 antikoerper, CHRNA7 antikoerper, cholinergic receptor nicotinic alpha 7 subunit antikoerper, neuronal acetylcholine receptor subunit alpha-7 antikoerper, cholinergic receptor, nicotinic, alpha 7 (neuronal) antikoerper, cholinergic receptor, nicotinic, alpha polypeptide 7 antikoerper, cholinergic receptor, nicotinic, alpha 7 antikoerper, CHRNA7 antikoerper, LOC100374356 antikoerper, chrna7 antikoerper, Chrna7 antikoerper, LOC100060521 antikoerper
- Hintergrund
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The protein encoded by CHRNA7 displays marked permeability to calcium ions and is a major component of brain nicotinic receptors that are blocked by, and highly sensitive to, alpha-bungarotoxin. Once this receptor binds acetylcholine, it undergoes an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. This gene is located in a region identified as a major susceptibility locus for juvenile myoclonic epilepsy and a chromosomal location involved in the genetic transmission of schizophrenia.
Alias Symbols: NACHRA7, CHRNA7-2
Protein Interaction Partner: ATXN1, ADCY6, PIK3R1, APP, FYN,
Protein Size: 502 - Molekulargewicht
- 56 kDa
- Gen-ID
- 1139
- NCBI Accession
- NM_000746, NP_000737
- UniProt
- P36544
- Pathways
- Synaptic Membrane
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