FXYD5 Antikörper (Middle Region)
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- Target Alle FXYD5 Antikörper anzeigen
- FXYD5 (FXYD Domain Containing Ion Transport Regulator 5 (FXYD5))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser FXYD5 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- SERPSPSTDV QTDPQTLKPS GFHEDDPFFY DEHTLRKRGL LVAAVLFITG
- Homologie
- Human: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against FXYD5. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human FXYD5
- Top Product
- Discover our top product FXYD5 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 178 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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FXYD5 modulates Na+ absorption and is increased in cystic fibrosis airway epithelia." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 294, Issue 4, pp. L654-64, (2008) (PubMed).
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FXYD5 modulates Na+ absorption and is increased in cystic fibrosis airway epithelia." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 294, Issue 4, pp. L654-64, (2008) (PubMed).
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- Target
- FXYD5 (FXYD Domain Containing Ion Transport Regulator 5 (FXYD5))
- Andere Bezeichnung
- FXYD5 (FXYD5 Produkte)
- Synonyme
- FXYD5 antikoerper, DYSAD antikoerper, IWU1 antikoerper, KCT1 antikoerper, OIT2 antikoerper, PRO6241 antikoerper, RIC antikoerper, EF-8 antikoerper, Oit2 antikoerper, FXYD domain containing ion transport regulator 5 antikoerper, FXYD domain-containing ion transport regulator 5 antikoerper, FXYD5 antikoerper, Fxyd5 antikoerper
- Hintergrund
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FXYD5 is a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. This gene product, FXYD5, has not been characterized as a protein. This reference sequence was derived from AF161462.1 and ESTs, validated by multiple replicate ESTs and human genomic sequence. This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. This gene product, FXYD5, has not been characterized as a protein. Two transcript variants have been found for this gene, and they are both predicted to encode the same protein. [RefSeq curation by Kathleen J. Sweadner, Ph.D., sweadner@helix.mgh.harvard.edu.].
Alias Symbols: HSPC113, IWU-1, IWU1, KCT1, OIT2, PRO6241, RIC, dysad, DYSAD
Protein Interaction Partner: UBC,
Protein Size: 178 - Molekulargewicht
- 19 kDa
- Gen-ID
- 53827
- NCBI Accession
- NM_014164, NP_054883
- UniProt
- Q96DB9
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