FXYD5 Antikörper (N-Term)

Produktnummer ABIN2780210

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-FXYD5 Antikörper wird verwendet zum Nachweis von FXYD5 in Proben von Human, Maus und Saccharomyces cerevisiae. Er wurde validiert für WB.

Kurzübersicht für FXYD5 Antikörper (N-Term) (ABIN2780210)

Target: FXYD5 (FXYD Domain Containing Ion Transport Regulator 5 (FXYD5))

Reaktivität: Human, Maus, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FXYD5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FXYD5 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: FXYD5 Antibody - N-terminal region

Sequenz: LQPTSPTPTW PADETPQPQT QTQQLEGTDG PLVTDPETHK STKAAHPTDD

Homologie: Human: 100%, Mouse: 100%, Yeast: 90%

Produktmerkmale: This is a rabbit polyclonal antibody against FXYD5. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FXYD5

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP37690-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-FXYD5 Antikörper (ABIN2780210)

Song, Li, Sun, Zhao: "Fxyd5 activates the NF‑κB pathway and is involved in chondrocytes inflammation and extracellular matrix degradation." in: Molecular medicine reports, Vol. 25, Issue 4, (2022) (PubMed).

Details zu FXYD5

Target: FXYD5 (FXYD Domain Containing Ion Transport Regulator 5 (FXYD5))

Andere Bezeichnung: FXYD5

Hintergrund:

Background Information: FXYD5 is a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIon Channel (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIon Channel) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. This gene product, FXYD5, has not been characterized as a protein.

Gene Name: FXYD domain containing ion transport regulator 5

Alternative Symbols: RIC, IWU1, KCT1, OIT2, DYSAD, HSPC113, PRO6241

Protein Name: FXYD domain-containing ion transport regulator 5

Molekulargewicht: 20kDa

Gen-ID: 53827

NCBI Accession: NP_659003

UniProt: Q96DB9