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KCNJ11 Antikörper (Middle Region)
KCNJ11
Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN2776174
Produktdetails anti-KCNJ11 Antikörper
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Target
Alle KCNJ11 Antikörper anzeigen
KCNJ11
(Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11))
Bindungsspezifität
Alle Epitope für KCNJ11 Antikörper
Middle Region
Reaktivität
Alle Reaktivitäten für KCNJ11 Antikörper
Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)
Wirt
Alle Wirte für KCNJ11 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für KCNJ11 Antikörper
Polyklonal
Konjugat
Alle Konjugate für KCNJ11 Antikörper
Dieser KCNJ11 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für KCNJ11 Antikörper
Western Blotting (WB)
Sequenz
SMIISATIHM QVVRKTTSPE GEVVPLHQVD IPMENGVGGN SIFLVAPLII
Homologie
Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%
Produktmerkmale
This is a rabbit polyclonal antibody against KCNJ11. It was validated on Western Blot.
Aufreinigung
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of HUMAN KCNJ11
Top Product
Discover our top product KCNJ11 Primärantikörper
Alternativen
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anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11) (Center) antibody
KCNJ11
Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Schwein
WB, IHC, IF, IC
Wirt: Kaninchen
Polyclonal
unconjugated
Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeat freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Details zu KCNJ11
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Target
KCNJ11
(Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11))
Andere Bezeichnung
KCNJ11 (KCNJ11 Produkte )
Synonyme
kir6.2 antikoerper, Kir6.2 antikoerper, mBIR antikoerper, BIR antikoerper, HHF2 antikoerper, IKATP antikoerper, KIR6.2 antikoerper, PHHI antikoerper, TNDM3 antikoerper, potassium voltage-gated channel subfamily J member 11 antikoerper, potassium inwardly-rectifying channel, subfamily J, member 11 antikoerper, potassium inwardly rectifying channel, subfamily J, member 11 antikoerper, KCNJ11 antikoerper, kcnj11 antikoerper, Kcnj11 antikoerper
Hintergrund
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and is found associated with the sulfonylurea receptor SUR. Mutations in this gene are a cause of familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), an autosomal recessive disorder characterized by unregulated insulin secretion. Defects in this gene may also contribute to autosomal dominant non-insulin-dependent diabetes mellitus type II (NIDDM), transient neonatal diabetes mellitus type 3 (TNDM3), and permanent neonatal diabetes mellitus (PNDM). Alias Symbols: BIR, HHF2, IKATP, KIR6.2, PHHI, TNDM3 Protein Interaction Partner: YWHAB, UBC, ABCC9, AP2M1, KCNJ8, KCNJ2, ABCC8, LDHA, Protein Size: 303
Molekulargewicht
33 kDa
Gen-ID
3767
NCBI Accession
NM_001166290 , NP_001159762
Pathways
Negative Regulation of Hormone Secretion
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