EPB41 Antikörper (N-Term)

Produktnummer ABIN2775561

Produktdetails anti-EPB41 Antikörper

Target: EPB41 (Erythrocyte Membrane Protein Band 4.1 (Elliptocytosis 1, RH-Linked) (EPB41))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen, Hund, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EPB41 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SESRGLSRLF SSFLKRPKSQ VSEEEGKEVE SDKEKGEGGQ KEIEFGTSLD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against EPB41. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EPB41

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 775 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu EPB41

Target: EPB41 (Erythrocyte Membrane Protein Band 4.1 (Elliptocytosis 1, RH-Linked) (EPB41))

Andere Bezeichnung: EPB41 (EPB41 Produkte)

Synonyme: P4.1R antikoerper, epb41 antikoerper, wu:fb70c02 antikoerper, EPB41 antikoerper, el1 antikoerper, 4.1r antikoerper, 4.1R antikoerper, EL1 antikoerper, HE antikoerper, AI415518 antikoerper, D4Ertd442e antikoerper, Elp-1 antikoerper, Elp1 antikoerper, Epb41 antikoerper, mKIAA4056 antikoerper, erythrocyte membrane protein band 4.1b antikoerper, erythrocyte membrane protein band 4.1 antikoerper, erythrocyte membrane protein band 4.1 L homeolog antikoerper, epb41b antikoerper, EPB41 antikoerper, epb41 antikoerper, epb41.L antikoerper, Epb41 antikoerper

Hintergrund: Elliptocytosis is a hematologic disorder characterized by elliptically shaped erythrocytes and a variable degree of hemolytic anemia. Inherited as an autosomal dominant, elliptocytosis results from mutation in any one of several genes encoding proteins of the red cell membrane skeleton. The form discussed here is the one found in the 1950s to be linked to Rh blood group and more recently shown to be caused by a defect in protein 4.1. 'Rh-unlinked' forms of elliptocytosis are caused by mutation in the alpha-spectrin gene, the beta-spectrin gene, or the band 3 gene.Elliptocytosis is a hematologic disorder characterized by elliptically shaped erythrocytes and a variable degree of hemolytic anemia. Inherited as an autosomal dominant, elliptocytosis results from mutation in any one of several genes encoding proteins of the red cell membrane skeleton. The form discussed here is the one found in the 1950s to be linked to Rh blood group and more recently shown to be caused by a defect in protein 4.1. 'Rh-unlinked' forms of elliptocytosis are caused by mutation in the alpha-spectrin gene (MIM 182860), the beta-spectrin gene (MIM 182870), or the band 3 gene (MIM 109270).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-95 BM465039.1 1-95 96-2238 J03796.1 40-2182 2239-2780 AL833483.1 1799-2340 2781-2943 BU184161.1 560-722 2944-3952 AL833483.1 2504-3512 3953-4352 BM997767.1 226-625 4353-4796 BE257308.1 115-558 4797-5656 BC009063.1 442-1301 5657-6064 BM740451.1 1-408 c
Alias Symbols: 4.1R, EL1, HE
Protein Interaction Partner: CLNS1A, ZCCHC10, RWDD2B, CALM, UBC, FN1, Htt, MACROD1, C2CD2L, CENPJ, TJP2, EIF3G, SMAD3, SEC14L1, YWHAB, DLG1, KPNA2, CASK, GDI1, U2AF2, U2AF1, TUBA4A, TPM1, FKBP2, SPTB, SPTAN1, SPTBN1, EPB42, PRKCB, NUMA1, MYL1, YWHAQ, EGFR, DRD3, DRD2, CRYAB, BCAM, GY
Protein Size: 775

Molekulargewicht: 85 kDa

Gen-ID: 2035

NCBI Accession: NM_203343, NP_976218

UniProt: Q4VB86