EPB41 Antikörper (pTyr418, pTyr660)

Produktnummer ABIN7139042

Produktdetails anti-EPB41 Antikörper

Target: EPB41 (Erythrocyte Membrane Protein Band 4.1 (Elliptocytosis 1, RH-Linked) (EPB41))

Bindungsspezifität: pTyr418, pTyr660

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EPB41 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Human, Maus

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of tyrosine 660/418 (N-I-Y(p)-I-R)derived from Human EPB41.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:1000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu EPB41

Target: EPB41 (Erythrocyte Membrane Protein Band 4.1 (Elliptocytosis 1, RH-Linked) (EPB41))

Andere Bezeichnung: EPB41 (EPB41 Produkte)

Synonyme: P4.1R antikoerper, epb41 antikoerper, wu:fb70c02 antikoerper, EPB41 antikoerper, el1 antikoerper, 4.1r antikoerper, 4.1R antikoerper, EL1 antikoerper, HE antikoerper, AI415518 antikoerper, D4Ertd442e antikoerper, Elp-1 antikoerper, Elp1 antikoerper, Epb41 antikoerper, mKIAA4056 antikoerper, erythrocyte membrane protein band 4.1b antikoerper, erythrocyte membrane protein band 4.1 antikoerper, erythrocyte membrane protein band 4.1 L homeolog antikoerper, epb41b antikoerper, EPB41 antikoerper, epb41 antikoerper, epb41.L antikoerper, Epb41 antikoerper

Hintergrund:

Background:

Elliptocytosis is a hematologic disorder characterized by elliptically shaped erythrocytes and a variable degree of hemolytic anemia. Inherited as an autosomal dominant, elliptocytosis results from mutation in any one of several genes encoding proteins of the red cell membrane skeleton. The form discussed here is the one found in the 1950s to be linked to Rh blood group and more recently shown to be caused by a defect in protein 4.1. 'Rh-unlinked' forms of elliptocytosis are caused by mutation in the alpha-spectrin gene, the beta-spectrin gene, or the band 3 gene.

Conboy J.G., Proc. Natl. Acad. Sci. U.S.A. 83:9512-9516(1986).
Tang T.K., Adv. Exp. Med. Biol. 241:81-95(1988).
Tang T.K., Proc. Natl. Acad. Sci. U.S.A. 85:3713-3717(1988).

Aliases: 4.1R antibody, 41_HUMAN antibody, Band 4.1 antibody, E41P antibody, EL 1 antibody, EL1 antibody, EL1 gene antibody, Elliptocytosis 1 antibody, Elliptocytosis 1 RH linked antibody, EPB 4.1 antibody, EPB 41 antibody, EPB4.1 antibody, Epb41 antibody, Erythrocyte membrane protein band 4.1 (elliptocytosis 1 RH linked) antibody, Erythrocyte membrane protein band 4.1 antibody, Erythrocyte surface protein band 4.1 antibody, HE antibody, P4.1 antibody, Protein 4.1 antibody, Protein 4.1, red blood cell type antibody

UniProt: P11171