TMC8 Antikörper (N-Term)

Produktnummer ABIN2774034

Produktdetails anti-TMC8 Antikörper

Target: TMC8 (Transmembrane Channel-Like 8 (TMC8))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TMC8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PGPTLNLTLQ CPGSRQSPPG VLRFHNQLWH VLTGRAFTNT YLFYGAYRVG

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TMC8. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TMC8

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 726 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TMC8

Target: TMC8 (Transmembrane Channel-Like 8 (TMC8))

Andere Bezeichnung: TMC8 (TMC8 Produkte)

Synonyme: EV2 antikoerper, EVER2 antikoerper, EVIN2 antikoerper, Ever2 antikoerper, mFLJ00400 antikoerper, transmembrane channel like 8 antikoerper, transmembrane channel-like 8 antikoerper, transmembrane channel-like gene family 8 antikoerper, TMC8 antikoerper, Tmc8 antikoerper

Hintergrund: Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 8 predicted transmembrane domains and 3 leucine zipper motifs.
Alias Symbols: EV2, EVER2, EVIN2, MGC102701, MGC40121
Protein Interaction Partner: TRAF2, TRAF1,
Protein Size: 726

Molekulargewicht: 82 kDa

Gen-ID: 147138

NCBI Accession: NM_152468, NP_689681

UniProt: Q8IU68